Reference : Use of specific bioluminescent cell lines for the detection of steroid hormone (ant)agon...
Scientific journals : Article
Physical, chemical, mathematical & earth Sciences : Chemistry
http://hdl.handle.net/2268/8708
Use of specific bioluminescent cell lines for the detection of steroid hormone (ant)agonists in meat producing animals
English
Willemsen, Philippe [> > > >]
Scippo, Marie-Louise mailto [Université de Liège - ULg > Département de sciences des denrées alimentaires > Analyse des denrées alimentaires >]
Maghuin-Rogister, Guy mailto [Université de Liège - ULg > Département de sciences des denrées alimentaires > Département de sciences des denrées alimentaires >]
Martial, Joseph mailto [Université de Liège - ULg > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire >]
Muller, Marc mailto [Université de Liège - ULg > Département des sciences de la vie > Biologie et génétique moléculaire >]
2002
Analytica Chimica Acta
Elsevier Science Bv
473
1-2
119-126
Yes (verified by ORBi)
International
0003-2670
1873-4324
Amsterdam
[en] bioluminescence ; luciferase reporter gene ; steroid hormones ; transcription ; food ; residues ; progesterone ; dexamethasone ; liver
[en] We present stable transformed human mammary cell lines displaying highly inducible steroid receptor-mediated luciferase reporter gene expression. The utilization of a cell-based assay for detection of steroid agonists and antagonists down to 0.3 ng g(-1) is described and its application to the analysis of bovine samples is discussed. In particular, the use of the assays to detect illegal progesterone or androgen treatment has to take into account the presence of natural endogenous hormones. (C) 2002 Elsevier Science B.V. All rights reserved.
http://hdl.handle.net/2268/8708

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