Histomycologie unguéale

[en] The diversity of onychomycoses is large when the disease is scrutinized using traditional, fluorescence or confocal microscopy. Histomycology is a non-invasive assessment performed on nail clippings. The location of and the density in fungal cells is variable. In some instances, these aspects remain clinically unsuspected. In vivo confocal microscopy can bring the same information. Computerized image analysis of histological sections is the most performant means for quantifying the fungal load. Immunohistochemistry brings information about the identity of the fungus or the association of different fungi present in the nail plate. Mixed infections may be unifocal or located at different levels in the nail apparatus. The viability of fungi as assessed by vital stains can be assessed under the microscope and quantified by flow cytometry. The different facets of nail histomycology are complementary and shed some light on aspects sometimes unsuspected of onychomycoses.

Disciplines :

Dermatology

Author, co-author :

Arrese Estrada, Jorge ; Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie

Quatresooz, Pascale ; Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie

Franchimont, Claudine ; Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie

Pierard, Gérald ; Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie

Language :

French

Title :

Histomycologie unguéale

Publication date :

2003

Journal title :

Annales de Dermatologie et de Vénéréologie

ISSN :

0151-9638

Publisher :

Masson, Paris, France

Volume :

130

Pages :

1254-1259

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 12 March 2009

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Bibliography

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