ORBi: Diez Marianne - Evolution of blood parameters during weight loss in experimental obese Beagle dogs.

Reference : Evolution of blood parameters during weight loss in experimental obese Beagle dogs.


	Document type :	Scientific journals : Article
	Discipline(s) :	Life sciences : Veterinary medicine & animal health
	To cite this reference:	http://hdl.handle.net/2268/8471

Title :	Evolution of blood parameters during weight loss in experimental obese Beagle dogs.
Language :	English
Author, co-author :	Diez, Marianne [Université de Liège - ULg > Département de productions animales > Nutrition des animaux domestiques >]
	Michaux, Charles [Université de Liège - ULg > Département de productions animales > Biostatistique, économie, sélection animale >]
	Jeusette, Isabelle [> > > >]
	Baldwin, Paule [> > > >]
	Istasse, Louis [Université de Liège - ULg > Département de productions animales > Nutrition des animaux domestiques >]
	Biourge, Vincent [> > > >]
Publication date :	2004
Journal title :	Journal of Animal Physiology & Animal Nutrition
Publisher :	Blackwell Publishing
Volume :	88
Issue/season :	3-4
Pages :	166-71
Audience :	International
ISSN :	0931-2439
e-ISSN :	1439-0396
City :	Oxford
Country :	United Kingdom
Keywords :	[en] Animals ; Cholesterol/blood ; Dietary Fiber/administration & dosage/metabolism ; Dietary Proteins/administration & dosage/metabolism ; Dog Diseases/blood ; Dogs ; Fatty Acids, Nonesterified/blood ; Female ; Male ; Obesity/blood/veterinary ; Random Allocation ; Starch/administration & dosage ; Triglycerides/blood ; Weight Loss/physiology
Abstract :	[en] The effects of weight loss on hormonal and biochemical blood parameters were measured monthly [carnitine, creatinine, urea, free T4 (fT4), total T4 (TT4), plasma alkaline phosphatases (ALP), aspartate aminotransferase (AST), alanine aminotransferase (ALT), potassium and total proteins] or bimonthly [cholesterol, triglycerides, non-esterified fatty acids (NEFA), insulin-like growth factor I (IGF-I), glucose, insulin] in eight obese Beagles dogs fed either a high protein dry diet, DP (crude protein 47.5%, on dry matter basis) or a commercial high fibre diet, HF (crude protein 23.8%, crude fibre 23.3%). The dogs were allotted to two groups according to sex and body weight (BW) and they were respectively fed with the DP or the control HF diet during 12-26 weeks, until they reach their optimal BW. The plasma basal triglycerides and cholesterol concentrations were decreased by the two diets but the difference was only significant for the DP diet. The plasma mean NEFA concentration increased regularly over the period with the HF diet, without significant difference between the two diets. No effect of diet or weight loss was observed on plasma carnitine, urea, creatinine, ALP, AST, ALT, potassium, TT4, FT4, IGF-I, glucose and insulin. Weight loss induced a decrease in fT4 plasma concentration (p < 0.001). The high protein diet allowed a safe weight loss.
Funders :	Royal Canin, France
Target :	Researchers ; Professionals
Permalink :	http://hdl.handle.net/2268/8471
DOI :	10.1111/j.1439-0396.2003.00474.x

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