[en] A decline of cognitive functioning affecting several cognitive domains was frequently reported in patients with frontotemporal dementia. We were interested in determining if these deficits can be interpreted as reflecting an impairment of controlled cognitive processes by using an assessment tool specifically developed to explore the distinction between automatic and controlled processes, namely the process dissociation procedure (PDP) developed by Jacoby [1]. The PDP was applied to a word stem completion task to determine the contribution of automatic and controlled processes to episodic memory performance and was administered to a group of 12 patients with the behavioural variant of frontotemporal dementia (bv-FTD) and 20 control subjects (CS). Bv-FTD patients obtained a lower performance than CS for the estimates of controlled processes, but no group differences was observed for estimates of automatic processes. The between-groups comparison of the estimates of controlled and automatic processes showed a larger contribution of automatic processes to performance in bv-FTD, while a slightly more important contribution of controlled processes was observed in control subjects. These results are clearly indicative of an alteration of controlled memory processes in bv-FTD.
Research center :
GIGA CRC (Cyclotron Research Center) In vivo Imaging-Aging & Memory - ULiège Centre de Neurosciences Cognitives et Comportementales - ULiège
Disciplines :
Neurosciences & behavior
Author, co-author :
Collette, Fabienne ; Université de Liège - ULiège > Département des sciences cognitives > Neuropsychologie
Van der Linden, Martial ; Université de Liège - ULiège > Département des sciences cognitives > Psychopathologie cognitive
Salmon, Eric ; Université de Liège - ULiège > Département des sciences cliniques > Neuroimagerie des troubles de la mémoire et révalid. cogn.
Language :
English
Title :
Dissociation between controlled and automatic processes in the behavioral variant of fronto-temporal dementia
Jacoby LL(1991) A process dissociation framework: Separating automatic from intentional uses of memory. J Mem Lang 30, 513-541.
Perry RJ, Graham A, Williams G, Rosen H, Erzinclioglu SW, Weiner M, Miller B, Hodges J (2006) Patterns of frontal lobe atrophy in frontotemporal dementia: A volumetric MRI study. Dement Geriatr Cogn Disord 22, 278-287.
Rosen HJ, Gorno-Tempini ML, Goldman WP, Perry RJ, Schuff N, Weiner M, al e (2002) Patterns of brain atrophy in fron- totemporal dementia and semantic dementia. Neurology 58, 198-208.
Grossman M (2002) Frontotemporal dementia: A review. J Int Neuropsychol Soc 8, 566-583.
Bozeat S, Gregory CA, Lambon Ralph MA, Hodges JR (2000) Which neuropsychiatric and behavioural features distinguish frontal and temporal variants of frontotemporal dementia from Alzheimer's disease? J Neurol Neurosurg Psychiatry 69, 178-186.
Harciarek M, Jodzio K (2005) Neuropsychological differences between frontotemporal dementia and Alzheimer's disease: A review. Neuropsychol Rev 15, 131-145.
Diehl-Schmid J, Pohl C, Perneczky R, Forstl H, Kurz A (2006) Behavioral disturbances in the course of frontotemporal dementia. Dement Geriatr Cogn Disord 22, 532-537.
Hodges JR, Patterson K, Ward R, Garrard P, Bak T, Perry R, Gregory C (1999) The differentiation of semantic dementia and frontal lobe dementia (temporal and frontal variants of frontotemporal dementia) from early Alzheimer's disease: A comparative neuropsychological study. Neuropsychology 13, 31-40.
Kramer JH, Jurik J, Sha SJ, Rankin KP, Rosen HJ, Johnson JK, Miller BL (2003) Distinctive neuropsychological patterns in frontotemporal dementia, semantic dementia, and Alzheimer disease. Cogn Behav Neurol 16, 211-218.
Wittenberg D, Possin KL, Rascovsky K, Rankin KP, Miller BL, Kramer JH (2008) The early neuropsychological and behavioral characteristics of frontotemporal dementia. Neuropsychol Rev 18, 91-102.
Matuszewski V, Piolino P, de la Sayette V, Lalevee C, Pelerin A, Dupuy B, Viader F, Eustache F, Desgranges B (2006) Retrieval mechanisms for autobiographical memories: insights from the frontal variant offrontotemporal dementia. Neuropsy- chologia 44, 2386-2397.
Pasquier F, Grymonprez L, Lebert F, Van der Linden M (2001) Memory impairment differs in frontotemporal dementia and Alzheimer's disease. Neurocase 7, 161-171.
Pachana NA, Brauer Boone K, Miller BL, Cummings JL, Berman N (1996) Comparison of neuropsychological functioning in Alzheimer's disease and frontotemporal dementia. J Int Neuropsychol Soc 2, 505-510.
Perry RJ, Hodges JR(2000) Differentiating frontal andtempo- ral variant frontotemporal dementia from Alzheimer's disease. Neurology 54, 2277-2284.
Bastin C, Van der Linden M (2003) The contribution ofrecol- lection and familiarity to recognition memory: A study ofthe effects of test format and aging. Neuropsychology 17, 14-24.
Soderlund H, Black SE, Miller BL, Freedman M, Levine B (2008) Episodic memory and regional atrophy in frontotem- poral lobar degeneration. Neuropsychologia 46, 127-136.
Glosser G, Gallo JJ, Clark CM, Grossman M (2002) Memory encoding and retrieval in frontotemporal dementia and Alzheimer's disease. Neuropsychology 16, 190-196.
Baddeley AD (1986) Working memory, Clarendon Press, Oxford.
Collette F, Amieva H, Adam S, Hogge M, Van der Linden M, Fabrigoule C, Salmon E (2007) Comparison of inhibitory functioning in mild Alzheimer's disease and frontotemporal dementia. Cortex 43, 866-874.
Giovagnoli AR, Erbetta A, Reati F, Bugiani O (2008) Differential neuropsychological patterns of frontal variant fron- totemporal dementia and Alzheimer's disease in a study of diagnostic concordance. Neuropsychologia 46, 1495-1504.
Gregory C, Lough S, Stone V, Erzinclioglu S, Martin L, Baron- Cohen S, Hodges JR (2002) Theory of mind in patients with frontal variant frontotemporal dementia and Alzheimer's disease: theoretical and practical implications. Brain 125, 752764.
Lough S, Kipps CM, Treise C, Watson P, Blair JR, Hodges JR (2006) Social reasoning, emotion and empathy in frontotem- poral dementia. Neuropsychologia 44, 950-958.
Gregory CA, Serra-Mestres J, Hodges JR (1999) Early diagnosis of the frontal variant of frontotemporal dementia: how sensitive are standard neuroimaging and neuropsychologic tests. Neuropsychiatry Neuropsychol BehavNeurol 12, 128-135.
Neary D, Snowden JS, Northen B, Goulding P (1988) Dementia of frontal lobe type. J Neurol Neurosurg Psychiatry 51, 353-361.
Snowden JS, Neary D, Mann DMA (1996) Fronto-temporal lobar degeneration: Fronto-temporal dementia, progressive aphasia, semantic dementia, Churchill Livingstone, New York.
Rascovsky K, Salmon DP, Ho GJ, Galasko D, Peavy GM, Hansen LA, Thal LJ (2002) Cognitive profiles differ in autopsy-confirmed frontotemporal dementia and AD. Neurology 58, 1801-1808.
Piolino P, Chetelat G, Matuszewski V, Landeau B, Mezenge F, Viader F, de la Sayette V, Eustache F, Desgranges B (2007) In search of autobiographical memories: A PET study in the frontal variant of frontotemporal dementia. Neuropsychologia 45, 2730-2743.
Hasher L, Zacks R (1979) Automatic and effortful processes in memory. J Exp Psychol General 108, 356-388.
Neary D, Snowden JS, Gustafson L, Passant U, Stuss D, Black S, Freedman M, Kertesz A, Robert PH, Albert M, Boone K, Miller ML, Cummings J, Benson DF (1998) Frontotemporal lobar degeneration. A consensus on clinical diagnostic criteria. Neurology 51, 1546-1554.
Kipps CM, Nestor PJ, Fryer TD, Hodges JR (2007) Behavioural variant frontotemporal dementia: not all it seems? Neurocase 13, 237-247.
Mattis S (1973) Dementia Rating Scale. NFER-Nelson, Windsor.
Yeasavage JA, Brink TL, Rose TL, Lum O (1983) Development and validation of a geriatric depression screening scale: A preliminary report. J Psychiatric Res 17, 37-49.
Zigmond AS, Snaith RP (1983) The hospital anxiety and depression scale. Acta Psychiatr Scand 67, 361-370.
Stroop JR (1935) Studies of interference in serial verbal reactions. J Exp Psychology 6, 643-661.
Burgess PW, Shallice T (1996) Response suppression, initiation and strategy use following frontal lobe lesions. Neuropsy- chologia 34, 263-273.
Reitan RM, Wolfson D (1995) Category test and trail making test as measures of frontal lobe functions. Clin Neuropsychol- ogist 9, 50-56.
Freedman M, Oscar-Berman M (1986) Bilateral frontal lobe disease and selective DR deficits in humans. Behav Neurosci 100, 337-342.
Burgess PW, Shallice T (1996) Bizarres responses, rule detection and frontal lobe lesions. Cortex 32, 241-259.
Belleville S, Peretz I, Malenfant D (1996) Examination of the working memory components in normal aging and in dementia of the Alzheimer type. Neurospychologia 34, 195-207.
Salthouse TA, Babcock RL (1991) Decomposing adult age differences in working memory. Dev Psychology 27, 763-776.
Barrash J, Anderson SW, Jones RD, Tranel D (1997) in 25th Annual Meeting of the International Neuropsychological Society (Orlando, FL).
Rochat L, Ammann J, Mayer E, Annoni J-M, Van der Linden M (2009) Executive disorders and perceived socio-emotional changes after traumatic brain injury. J Neuropsychol 3, 213227.
Cohen J (1988) Statistical power analysis for the behavioral sciences, Lawrence Erlbaum Associates, Hillsdale,NJ.
Hay JF, Jacoby LL (1999) Separating habits and recollection in young and older adults: Effects of elaborative processing and distinctiveness. Psychology Aging 14, 122-134.
Adam S, Van der Linden M, Collette F, Lemauvais L, Salmon E (2005) Further exploration of controlled and automatic processes in early Alzheimer's disease. Neuropsychology 19, 420427.
Koivisto M, Portin R, Seinela A, Rinne J (1998) Automatic influences of memory in Alzheimer's disease. Cortex 34, 209219.
Lehto J (1996) Are executive function tests dependent on working memory capacity? The Q J Exp Psychology 49A, 29-50.
Lowe C, Rabbit P (1997) Cognitive models of aging and frontal lobe deficits. In Methodology offrontal and executive functions., Rabbitt P, ed. Psychology Press, Hove, pp. 39-59.
Robbins TW, Owen AM, Sahakian BJ, Lawrence AD, McInnes L, Rabbitt PMA (1998) A study of performance on tests from the CANTAB battery sensitive to frontal lobe dysfunction in a large sample of normal volunteers: implications for theories ofexecutive functioning and cognitive aging. J Int Neuropsychol Soc 4, 474-490.
Burgess PW (1997) Theory and methodology in executive function research. In Methodology of frontal and executive functions, Rabbit P, ed. Psychology Press, Hove, pp. 81-116.
Burgess PW, Alderman N, Evans J, Emslie H, Wilson BA (1998) The ecological validity of tests of executive functions. JIntNeuropsychol Soc 4, 547-558.
Duncan J, Johnson R, Swales M, Freer C (1997) Frontal lobe deficits after head injury: Unity and diversity of function. Cogn Neuropsychol 14, 713-741.
Yesavage JA, Brink TL, Rose TL, Lum O, Huang V, Adey M, Leirer VO (1983) Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatry Res 17, 37-49.
