Article (Scientific journals)
Influence of Age and Breed on the Binding of Oxygen to Red Blood Cells of Bovine Calves
Gustin, Pascal; Detry, B.; Robert, Alain et al.
1997In Journal of Applied Physiology, 82 (3), p. 784-90
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Abstract :
[en] The influence of somatic growth and genetic selection on the whole blood oxygen equilibrium curve (OEC) was measured under standard conditions in double-muscled and dairy calves during their first 3 mo of life. Crossbreed animals were also investigated. Hemoglobin, 2,3-diphosphoglycerate (DPG), Cl, and Pi concentrations were also measured. The percentage of fetal hemoglobin (HbF) was determined. The influence of exogenous Cl, Pi, and pH on the OEC was also assessed. The PO2 at 50% hemoglobin saturation (P50) increased during somatic growth, probably because of the increase in DPG recorded in double-muscled neonates and to the progressive disappearance of HbF in both breeds. The oxygen exchange fraction (OEF%) was used to assess the combined influence of the OEC shift and OEC shape changes on blood oxygen desaturation under standard conditions, when the PO2 decreases within a physiological range. The OEF% showed an increase during the first month, then a stabilization. The effects of Cl, Pi, and pH in Friesian calves were similar as in adult cattle. Double-muscled neonates had a lower P50, OEF% values, and DPG concentrations and higher hemoglobin and Cl concentrations than Friesian neonates. The Pi concentration and the percentage of HbF were similar in both breeds. The pH and the Cl concentration had significantly less effect on the OEC in double-muscled than in Friesian calves. Crossbreed animals exhibited intermediate parameter values, between those recorded for double-muscled and Friesian calves. All differences between breeds progressively disappeared during the first month. These data show that blood function changes markedly in calves during the first month of life and that genetic selection can alter blood function.
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Gustin, Pascal ;  Université de Liège - ULiège > Département de sciences fonctionnelles > Pharmacologie, pharmacothérapie et toxicologie
Detry, B.
Robert, Alain 
Cao, M. L.
Lessire, Françoise  ;  Université de Liège - ULiège > Département clinique des animaux de production (DCP) > Médecine interne des équidés, des ruminants et des porcs
Cambier, Carole ;  Université de Liège - ULiège > Département de sciences fonctionnelles > Département de sciences fonctionnelles
Katz, V.
Ansay, Michel ;  Université de Liège - ULiège > Services généraux (Faculté de médecine vétérinaire) > Relations académiques et scientifiques (Méd. vétérinaire)
Frans, A.
Clerbaux, T.
Language :
English
Title :
Influence of Age and Breed on the Binding of Oxygen to Red Blood Cells of Bovine Calves
Publication date :
1997
Journal title :
Journal of Applied Physiology
ISSN :
8750-7587
eISSN :
1522-1601
Publisher :
American Physiological Society, United States - Maryland
Volume :
82
Issue :
3
Pages :
784-90
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 10 March 2009

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