Reference : Action of Patulin on Yeast

	Document type :	Scientific journals : Article
	Discipline(s) :	Life sciences : Microbiology
	To cite this reference:	http://hdl.handle.net/2268/82145

Title :	Action of Patulin on Yeast
Language :	English
Author, co-author :	Sumbu [ > > ]
	Thonart, Philippe [Université de Liège - ULg > Département des sciences de la vie > Biochimie et microbiologie industrielles - Bio-industries >]
	Bechet, J. [ > > ]
Publication date :	1983
Journal title :	Applied & Environmental Microbiology
Publisher :	American Society for Microbiology (ASM)
Volume :	45
Pages :	110-115
Audience :	International
ISSN :	0099-2240
e-ISSN :	1098-5336
City :	Washington
Country :	DC
Abstract :	[en] The action of patulin on Saccharomyces cerevisiae was studied. At weak doses, the drug inhibited growth, but inhibition was transient. After 10 min, syntheses of rRNA, tRNA, and probably mRNA were blocked; this was shown by radioactive precursor incorporation assays and gel electrophoresis of RNAs. After recovery of growth, patulin disappeared from the medium. It seemed that this degradation resulted from the activity of an inducible enzymatic system. Induced cells resisted very high patulin concentrations.
Permalink :	http://hdl.handle.net/2268/82145

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