Reference : Two distinct neuronal networks mediate the awareness of environment and of self
Scientific journals : Article
Social & behavioral sciences, psychology : Neurosciences & behavior
Human health sciences : Neurology
http://hdl.handle.net/2268/81391
Two distinct neuronal networks mediate the awareness of environment and of self
English
Vanhaudenhuyse, Audrey mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Demertzi, Athina mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Schabus, Manuel mailto [> >]
Noirhomme, Quentin mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Brédart, Serge mailto [Université de Liège - ULg > Département de Psychologie : cognition et comportement > Psychologie cognitive >]
Boly, Mélanie mailto [Université de Liège - ULg > Département des sciences cliniques > Neurologie >]
Phillips, Christophe mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Soddu, Andrea mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Luxen, André mailto [Université de Liège - ULg > Département de chimie (sciences) > Chimie organique de synthèse >]
MOONEN, Gustave mailto [Centre Hospitalier Universitaire de Liège - CHU > > Neurologie Sart Tilman >]
Laureys, Steven mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
2011
Journal of Cognitive Neuroscience
MIT Press
23
3
570-578
Yes (verified by ORBi)
International
0898-929X
1530-8898
Cambridge
United Kingdom
[en] Evidence from functional neuroimaging studies on resting state suggests that there are two distinct anticorrelated cortical systems that mediate conscious awareness: an "extrinsic" system that encompasses lateral fronto-parietal areas and has been linked with processes of external input (external awareness), and an "intrinsic" system which encompasses mainly medial brain areas and has been associated with internal processes (internal awareness). The aim of our study was to explore the neural correlates of resting state by providing behavioral and neuroimaging data from healthy volunteers. With no a priori assumptions, we first determined behaviorally the relationship between external and internal awareness in 31 subjects. We found a significant anticorrelation between external and internal awareness with a mean switching frequency of 0.05 Hz (range: 0.01-0.1 Hz). Interestingly, this frequency is similar to BOLD fMRI slow oscillations. We then evaluated 22 healthy volunteers in an fMRI paradigm looking for brain areas where BOLD activity correlated with "internal" and "external" scores. Activation of precuneus/posterior cingulate, anterior cingulate/mesiofrontal cortices, and parahippocampal areas ("intrinsic system") was linearly linked to intensity of internal awareness, whereas activation of lateral fronto-parietal cortices ("extrinsic system") was linearly associated with intensity of external awareness.
Centre de Recherches du Cyclotron - CRC
Fonds de la Recherche Scientifique (Communauté française de Belgique) - F.R.S.-FNRS ; the European Commission ; The James McDonnell Foundation ; the Mind Science Foundation ; The French Speaking Community Concerted Research Action ; Fondation Médicale Reine Elisabeth ; DISCOS Marie-Curie Research Training Network,
http://hdl.handle.net/2268/81391
also: http://hdl.handle.net/2268/94341
10.1162/jocn.2010.21488

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Open access
Demertzi_JCognNeurosci2010.pdfPublisher postprint208.35 kBView/Open

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.