Reference : Supporting cell cytoskeleton during development of the organ of Corti in rat
Scientific congresses and symposiums : Poster
Life sciences : Biochemistry, biophysics & molecular biology
http://hdl.handle.net/2268/80517
Supporting cell cytoskeleton during development of the organ of Corti in rat
English
[fr] Localisation du cytosquelette au sein des cellules de soutien durant le dévelopemment de l'organe de Corti chez le rat
Johnen, Nicolas mailto [Université de Liège - ULg > Département des sciences de la vie > Biologie cellulaire >]
Thelen, Nicolas mailto [Université de Liège - ULg > Département des sciences de la vie > Biologie cellulaire >]
Malgrange, Brigitte mailto [Université de Liège - ULg > > GIGA - Neurosciences - Neurologie >]
Thiry, Marc mailto [Université de Liège - ULg > Département des sciences de la vie > Biologie cellulaire >]
11-May-2009
No
No
National
The 8th bi-annual meeting of the Belgian Society for Neuroscience
11 mai 2009
Université de Liège
Liège
Belgium
[en] Auditory Organ ; Cytoskeleton ; Development
[en] The mammalian auditory organ, the organ of Corti (OC), is composed of mechanosensory hair cells and nonsensory supporting cell types. Based on their morphology and physiology, a least four types of supporting cells can be identified in the OC: inner pillar cell, outer pillar cell, phalangeal cell and Deiter’s cells. All supporting cells are highly specialized cells that are characterized by the presence of bundled microtubules with 15 protofilaments instead of 13. Using antibobies against different proteins of cytoskeleton (tubulin, cutokeratin and vimentin), we investigated by confocal microscopy the setting up of supporting cells' cytoskeleton during the differentiation of the OC in art from the embryonic day 18 (E18) to the postnatal 15 (P15). We showed that the inner pillar cells are labelled with an anti-beta IV tubulin from P0. Using an antibody to cytokeratin, a labelling appeared in Deiters' cells from E22. We also revealed that during the development of the OC, supporting cells were labelled with an anti-vimentin antibody from P0.
Giga-Neurosciences
Fonds de la Recherche Scientifique (Communauté française de Belgique) - F.R.S.-FNRS
Localisation spatiotemporelle du cytosquelette dans les cellules du canal cochléaire chez le rat entre le 18e jour embryonnaire et le 15e jour postnatal
Researchers ; Professionals ; Students
http://hdl.handle.net/2268/80517

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