Article (Scientific journals)
Renal transplantation from living related donors: a single center experience in viet nam.
Ledinh, H.; Detry, Olivier; Pham, M. S. et al.
2010In Transplantation Proceedings, 42 (10), p. 4389-91
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Abstract :
[en] INTRODUCTION: End-stage renal disease is a major public health problem in Viet Nam. A cooperative project between the University of Liege, Belgium, and the University of Medicine Pham Ngoc Thach, Ho Chi Minh City, Viet Nam, has permitted the establishment of an autonomous program of renal transplantation from living-related donors at the Peoples' Hospital No 115. The aim of this paper was to report the primary results of the project and to draw conclusions for the future. PATIENTS AND METHODS: From January 2004 to July 2008, we performed 33 living-related renal transplantations. Mean ages of donors and recipients were 31.8 +/- 9.5 and 41.6 +/- 13.5 years, respectively. Laparoscopic nephrectomy was performed in 6 donors. The immunosuppressive regimen consisted of three drugs associated with induction therapy using anti-interleukin-2 receptor monoclonal antibody. RESULTS: The 33 donors are in good health at follow-up. Four developed major intra- or postoperative hemorrhage necessitating transfusion, with a surgical re-exploration in 1 donor. Wound infection occurred in 2 donors. Posttransplant recipient and graft survivals at 1 versus 3 years were 82% and 73% versus 82% and 65%, respectively. Eight recipients presented 13 biopsy-proven acute rejection episodes that were reversible in 7, but 1 patient lost his graft due to an irreversible rejection. Two recipients developed cancer. CONCLUSIONS: These initial results have encouraged us to continue the program of renal transplantation from living-related donors. However, they also pointed out the need to develop other donor sources.
Disciplines :
Surgery
Anesthesia & intensive care
Urology & nephrology
Author, co-author :
Ledinh, H.
Detry, Olivier  ;  Centre Hospitalier Universitaire de Liège - CHU > Chirurgie abdominale- endocrinienne et de transplantation
Pham, M. S.
Truong, H. M.
Tran, T. P.
Nguyen, P. K.
Ta, P. D.
Nguyen, C.
Huynh, T. N. N.
Bach, T. V.
Joris, Jean ;  Centre Hospitalier Universitaire de Liège - CHU > Anesthésie et réanimation
Bonvoisin, Catherine ;  Centre Hospitalier Universitaire de Liège - CHU > Néphrologie
De Roover, Arnaud ;  Centre Hospitalier Universitaire de Liège - CHU > Chirurgie abdominale- endocrinienne et de transplantation
Honore, Pierre ;  Centre Hospitalier Universitaire de Liège - CHU > Chirurgie abdominale- endocrinienne et de transplantation
Squifflet, Jean-Paul ;  Centre Hospitalier Universitaire de Liège - CHU > Chirurgie abdominale- endocrinienne et de transplantation
Meurisse, Michel ;  Centre Hospitalier Universitaire de Liège - CHU > Chirurgie abdominale- endocrinienne et de transplantation
More authors (6 more) Less
Language :
English
Title :
Renal transplantation from living related donors: a single center experience in viet nam.
Publication date :
December 2010
Journal title :
Transplantation Proceedings
ISSN :
0041-1345
eISSN :
1873-2623
Publisher :
Elsevier Science, New York, United States - New York
Volume :
42
Issue :
10
Pages :
4389-91
Peer reviewed :
Peer Reviewed verified by ORBi
Commentary :
Copyright (c) 2010 Elsevier Inc. All rights reserved.
Available on ORBi :
since 21 December 2010

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