Reference : Cystatin C or Creatinine for Detection of Stage 3 Chronic Kidney Disease in Anorexia Ner...
Scientific journals : Article
Human health sciences : Urology & nephrology
http://hdl.handle.net/2268/7951
Cystatin C or Creatinine for Detection of Stage 3 Chronic Kidney Disease in Anorexia Nervosa.
English
Delanaye, Pierre mailto [Centre Hospitalier Universitaire de Liège - CHU > > Néphrologie >]
Cavalier, Etienne mailto [Centre Hospitalier Universitaire de Liège - CHU > > Chimie médicale >]
Radermecker, Régis mailto [Université de Liège - ULg > Département des sciences cliniques > Diabétologie, nutrition et maladie métaboliques >]
Paquot, Nicolas mailto [Centre Hospitalier Universitaire de Liège - CHU > > Diabétologie,nutrition, maladies métaboliques >]
Depas, Gisèle mailto [Centre Hospitalier Universitaire de Liège - CHU > > Médecine nucléaire >]
Chapelle, Jean-Paul mailto [Centre Hospitalier Universitaire de Liège - CHU > > Chimie médicale >]
Scheen, André mailto [Université de Liège - ULg > Département des sciences cliniques > Diabétologie, nutrition et maladie métaboliques - Médecine interne générale >]
Krzesinski, Jean-Marie mailto [Centre Hospitalier Universitaire de Liège - CHU > > Néphrologie >]
2008
Nephron. Clinical Practice
S. Karger
110
3
c158-c163
Yes (verified by ORBi)
International
1660-2110
Swizterland
[en] Background: Patients with anorexia nervosa (AN) are at a high risk of renal failure. Chronic kidney disease (CKD) is often missed in these patients because the serum creatinine is a poor marker of kidney function. We studied the utility of cystatin C to detect renal failure in this population. Method: Twenty-seven AN patients were studied. Glomerular filtration rates (GFR) were measured with the chromium-51- ethylenediaminetetraacetate ((51)Cr-EDTA) method. We compared the ability of creatinine and cystatin C to detect stage 3 CKD (GFR below 60 ml/min) by ROC curve analysis. Results: In this cohort, there is no correlation between GFR and serum creatinine, but there is a significant correlation between cystatin C and GFR. By ROC analysis, the cystatin C concentration is better than the serum creatinine concentration for the detection of stage 3 CKD (area under the curve of 0.86 vs. 0.61, p = 0.05). Conclusion: Plasma cystatin C is better than serum creatinine in detecting stage 3 CKD in patients with AN.
http://hdl.handle.net/2268/7951
10.1159/000166607
http://content.karger.com/produktedb/produkte.asp?typ=fulltext&file=000166607
Copyright (c) 2008 S. Karger AG, Basel.

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