Article (Scientific journals)
Virus neutralising antibodies against 22 bovine viral diarrhoea virus isolates in vaccinated calves
Hamers, Claude; Di Valentin, Emmanuel; Dumont, Chloé et al.
2002In Veterinary Journal, 163 (1), p. 61-67
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Keywords :
vaccine; bovine; BVDV; antibodies; neutralising
Abstract :
[en] Seven of nine colostrum deprived calves, free from bovine viral diarrhoea virus (BVDV), were vaccinated with a commercially available vaccine containing two inactivated strains of BVDV, an inactivated strain of bovine herpesvirus-1 and modified-live strains of bovine respiratory syncytial virus and para-influenza-3 virus. The two other calves were kept as controls. The virus neutralising (VN) antibodies induced by vaccination were tested against 22 antigenically diverse BVDV isolates, including reference strains and field isolates, both cytopathic and non-cytopathic, as well as genotypes I and II. The strains were isolated in Belgium, France, Germany, the United Kingdom and the USA. While there were variations in the VN titres of the individual calves against all the strains, serum from the seven animals neutralised 20 or more of the strains tested. From the results, it can be concluded that the vaccine can stimulate the production of VN antibodies capable of neutralising a wide range of European and American isolates of BVDV, including genotypes I and II.
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Hamers, Claude ;  Université de Liège - ULiège > Département des maladies infectieuses et parasitaires (DMI) > Immunologie et vaccinologie
Di Valentin, Emmanuel  ;  Université de Liège - ULiège > Département des sciences de la vie > Virologie - Immunologie
Dumont, Chloé ;  Université de Liège - ULiège > Département de droit > Droit social
Lambot, Michel ;  Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Département des maladies infectieuses et parasitaires
Joris, E.
Genicot, B.
Pastoret, Paul-Pierre ;  Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Département des maladies infectieuses et parasitaires
Language :
English
Title :
Virus neutralising antibodies against 22 bovine viral diarrhoea virus isolates in vaccinated calves
Publication date :
January 2002
Journal title :
Veterinary Journal
ISSN :
1090-0233
eISSN :
1532-2971
Publisher :
Bailliere Tindall, London, United Kingdom
Volume :
163
Issue :
1
Pages :
61-67
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 13 December 2010

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