Reference : HCMV seroprevalence and associated risk factors in pregnat women, Havana City, 2007 to 2...
Scientific journals : Article
Human health sciences : Immunology & infectious disease
http://hdl.handle.net/2268/79227
HCMV seroprevalence and associated risk factors in pregnat women, Havana City, 2007 to 2008
English
Correa, C. B. [Institute of Tropical Medicine Pedro Kouri, Havana City, Cuba > Virology Department > > >]
Kouri, V. [Institute of Tropical Medicine Pedro Kouri, Havana City, Cuba > Virology Department > > >]
Verdasquera, D. [Institute of Tropical Medicine Pedro Kouri, Havana City, Cuba > Virology Department > > >]
Martinez, P. A. [Institute of Tropical Medicine Pedro Kouri, Havana City, Cuba > Virology Department > > >]
Alvarez, A. [Institute of Tropical Medicine Pedro Kouri, Havana City, Cuba > Virology Department > > >]
Aleman, Y. [Institute of Tropical Medicine Pedro Kouri, Havana City, Cuba > Virology Department > > >]
Perez, L. [Institute of Tropical Medicine Pedro Kouri, Havana City, Cuba > Virology Department > > >]
Viera, J. [Institute of Tropical Medicine Pedro Kouri, Havana City, Cuba > Virology Department > > >]
Gonzalez, R. [Institute of Tropical Medicine Pedro Kouri, Havana City, Cuba > Virology Department > > >]
Perez, E. [Genetics Department of Municipalities: Regla, Old Havana, Central Havana, Cuba > > > >]
Moro, I. [Genetics Department of Municipalities: Regla, Old Havana, Central Havana, Cuba > > > >]
Navarro, M. A. [Genetics Department of Municipalities: Regla, Old Havana, Central Havana, Cuba > > > >]
Melin, Pierrette mailto [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Microbiologie médicale et virologie médicale >]
Sep-2010
Prenatal Diagnosis
Wiley
30
9
888-92
Yes (verified by ORBi)
International
0197-3851
Chichester
United Kingdom
[en] HCMV ; pregnancy ; seroprevalence ; Cuba ; risk factors ; Cytomegalovirus
[en] Objective To prenatally identify pregnant women at risk of developing congenital infection due to human
cytomegalovirus (HCMV).
Methods One thousand one hundred and thirty-one pregnant women from three municipalities from Havana
City were serologically screened for HCMV infection (IgM/IgG, IgG avidity) from January 2007 to January
2008. Demographical, epidemiological, and clinical variables were correlated to serologic status to identify
predictors of seroconversion in pregnancy.
Results The majority of women were seropositive to HCMV (92.6%); 27 women (2.4%) developed HCMV
active infection during pregnancy, defined by the detection of IgG+ and IgM+ (7 women), IgM+ and IgG−
(2 women), and IgG seroconversion (18 women). Susceptibility of active HCMV infection during pregnancy
was associated with maternal age <20 years and nulligravidity. Primary infection was detected in 20 pregnant
women (1.8%), whereas 7 patients (0.6%) had active non-primary infection.
Conclusion Although pregnant women in Cuba have high seroprevalence rates for HCMV, those younger
than 20 years and nulligravidae are at risk of acquiring infection during pregnancy.
Région wallonne : Direction générale des Relations extérieures - DGRE
Epidémiologie cubaine de l’infection congénitale par le cytomegalovirus et diagnostic prénatal
http://hdl.handle.net/2268/79227

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