Article (Scientific journals)
Management of severe preeclampsia
Brichant, Géraldine; Dewandre, Pierre-Yves; Foidart, Jean-Michel et al.
2010In Acta Clinica Belgica, 65 (3), p. 163-169
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Keywords :
Severe preeclampsia; Eclampsia; HELLP
Abstract :
[en] Features of severe preeclampsia include severe proteinuric hypertension and symptoms of central nervous system dysfunction, hepatocellular injury, thrombocytopenia, oliguria, pulmonary oedema, cerebrovascular accident and severe intrauterine growth restriction. Women with severe preeclampsia must be hospitalized to confirm the diagnosis, to assess the severity of the disease, to monitor the progression of the disease and to try to stabilize the disease. Severe preeclampsia may be managed expectantly, in selected cases. The objective of expectant management in these patients is to improve neonatal outcome. Expectant management is based on antihypertensive treatment and prevention of end organ dysfunction. Antihypertensive treatment improves maternal outcome but has the potential to be deleterious for the foetus. Plasma volume expansion has been suggested for severe preeclampsia but trials failed to show any benefit. Magnesium sulfate is the anticonvulsivant of choice to treat or prevent eclampsia when indicated. Antenatal corticosteroids are recommended in severely preeclamptic women with 26-34 weeks gestation. Timing of delivery is based upon gestational age, severity of preeclampsia, maternal and foetal risks.
Disciplines :
Anesthesia & intensive care
Reproductive medicine (gynecology, andrology, obstetrics)
Author, co-author :
Brichant, Géraldine ;  Université de Liège - ULiège > Département des sciences cliniques > Labo de biologie des tumeurs et du développement
Dewandre, Pierre-Yves  ;  Université de Liège - ULiège > Anesthésie et réanimation
Foidart, Jean-Michel ;  Université de Liège - ULiège > Département des sciences cliniques > Gynécologie - Obstétrique - Labo de biologie des tumeurs et du développement
Brichant, Jean-François ;  Université de Liège - ULiège > Département des sciences cliniques > Anesthésie et réanimation
Language :
English
Title :
Management of severe preeclampsia
Publication date :
2010
Journal title :
Acta Clinica Belgica
ISSN :
0001-5512
Publisher :
Acta Clinica Belgica, Bruxelles, Belgium
Volume :
65
Issue :
3
Pages :
163-169
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 01 December 2010

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