ORBi: Kelly J. A. - X-ray studies of enzymes that interact with penicillins.

Reference : X-ray studies of enzymes that interact with penicillins.


	Document type :	Scientific journals : Article
	Discipline(s) :	Life sciences : Biochemistry, biophysics & molecular biology
	To cite this reference:	http://hdl.handle.net/2268/77968

Title :	X-ray studies of enzymes that interact with penicillins.
Language :	English
Author, co-author :	Kelly, J. A. [> > > >]
	Kuzin, A. P. [> > > >]
	Charlier, Paulette [Université de Liège - ULg > Département des sciences de la vie > Cristallographie des macromolécules biologiques >]
	Fonze, E. [> > > >]
Publication date :	1998
Journal title :	Cellular and Molecular Life Sciences : CMLS
Publisher :	Birkhäuser
Volume :	54
Issue/season :	4
Pages :	353-8
Audience :	International
ISSN :	1420-682X
e-ISSN :	1420-9071
City :	Basel
Country :	Switzerland
Keywords :	[en] Bacterial Proteins ; Carrier Proteins/chemistry/metabolism ; Crystallography, X-Ray ; Hexosyltransferases ; Models, Molecular ; Muramoylpentapeptide Carboxypeptidase/chemistry/metabolism ; Penicillin-Binding Proteins ; Penicillins/chemistry/metabolism ; Peptidyl Transferases ; X-Ray Diffraction/methods ; beta-Lactamases/chemistry/metabolism
Abstract :	[en] The technique of X-ray diffraction has been successfully applied to enzymes associated with peptidoglycan biosynthesis. The technique has taught us a great deal about the structures and catalytic mechanisms of penicillin-binding proteins and beta-lactamases. An insight into the structural basis for antibiotic resistance is given.
Permalink :	http://hdl.handle.net/2268/77968

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Open access	Kelly_CMLS_1998.pdf		Publisher postprint	7.34 MB	View/Open

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