Reference : Epidemiological evaluation of a monoclonal ELISA detecting antibodies against bovine leu...
Scientific journals : Article
Life sciences : Microbiology
Life sciences : Veterinary medicine & animal health
http://hdl.handle.net/2268/7744
Epidemiological evaluation of a monoclonal ELISA detecting antibodies against bovine leukaemia virus in serum pools.
English
Knapen, K. [> > > >]
Kerkhofs, P. [> > > >]
Thiry, Etienne mailto [Université de Liège - ULg > Département des maladies infectieuses et parasitaires > Virologie, épidémiologie et pathologie des maladies virales >]
Mammerickx, M. [> > > >]
1994
Epidemiology & Infection
Cambridge University Press
113
3
563-9
International
0950-2688
Cambridge
United Kingdom
[en] Animals ; Antibodies, Viral/blood ; Belgium/epidemiology ; Cattle ; Enzootic Bovine Leukosis/diagnosis/epidemiology ; Enzyme-Linked Immunosorbent Assay/veterinary ; Leukemia Virus, Bovine/immunology ; Predictive Value of Tests ; Sensitivity and Specificity
[en] Sensitivity, specificity and predictive values of an enzyme-linked immunosorbent assay (ELISA) for detecting antibodies against bovine leukaemia virus (BLV) were evaluated using a representative sample of 145 serum pools, comprising from 3 to 48 individual sera. The sample was constituted according to the frequency distribution of the negative and positive pools analysed during a screening involving the whole cattle population of Belgium. Sensitivity and specificity were estimated to 88.9% and 100% and the predicted negative and positive values were 99.9% and 100%, respectively. These results indicate the use of serum pools is suitable for the detection of BLV infected herds in eradication campaigns.
http://hdl.handle.net/2268/7744

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