Article (Scientific journals)
Current concepts in the pathology and epigenetics of endometrial carcinoma.
Arafa, Mohammad; Somja, Joan; Dehan, Pierre et al.
2010In Pathology, 42 (7), p. 613-7
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Abstract :
[en] In the Western world, endometrial carcinoma is the most common malignant tumour of the female genital tract and is the fourth most common cancer in women. Two different clinicopathological subtypes are recognised: the oestrogen-related (type I, endometrioid) and the non-oestrogen related (type II, non-endometrioid). This article reviews the epidemiology, risk factors, genetic alterations during endometrial carcinogenesis, features of tumours and precursors and early detection of the disease. Insights into the epigenetic alterations, with emphasis on DNA methylation during endometrial carcinogenesis, and their diagnostic value are also provided.
Research center :
Giga-Cancer - ULiège
Disciplines :
Oncology
Author, co-author :
Arafa, Mohammad;  Department of Pathology, Faculty of Medicine, Mansoura University, Egypt
Somja, Joan ;  Centre Hospitalier Universitaire de Liège - CHU > Anatomie pathologique
Dehan, Pierre ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques
Kridelka, Frédéric ;  Centre Hospitalier Universitaire de Liège - CHU > Gynécologie-Obstétrique
Goffin, Frédéric ;  Centre Hospitalier Universitaire de Liège - CHU > Gynécologie-Obstétrique CHR
Boniver, Jacques ;  Centre Hospitalier Universitaire de Liège - CHU > Anatomie pathologique
Delvenne, Philippe ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques
Language :
English
Title :
Current concepts in the pathology and epigenetics of endometrial carcinoma.
Publication date :
2010
Journal title :
Pathology
ISSN :
0031-3025
eISSN :
1465-3931
Publisher :
Taylor & Francis, Abingdon, United Kingdom
Volume :
42
Issue :
7
Pages :
613-7
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 25 November 2010

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