Reference : Blood pressure, the prevalence of cardiovascular diseases, and exposure to cadmium : a p...
Scientific journals : Article
Human health sciences : Public health, health care sciences & services
Human health sciences : Urology & nephrology
http://hdl.handle.net/2268/77267
Blood pressure, the prevalence of cardiovascular diseases, and exposure to cadmium : a population study
English
Staessen, J. [Katholieke Universiteit Leuven - KUL > Physiopathology > Hypertension and cardiovascular rehabilitation unit > >]
Amery, A. [Katholieke Universiteit Leuven - KUL > Physiopathology > Hypertension and cardiovascular rehabilitation unit > >]
Bernard, A. [Université Catholique de Louvain - UCL > Industrial Toxicology and Occupational Medicine Unit > > >]
Bruaux, P. [Ministry of Health and Social Affairs, Brusses, Belgium > Institute of Hygiene and Epidemiology > > >]
Buchet, J. P. [Université Catholique de Louvain - UCL > Industrial Toxicology and Occupational Mediine Unit > > >]
Bulpitt, C. J. [Royal Postgraduate Medical School - Hammersmith Hospital, London, UK > Medicine > Geriatric medicie > >]
Claeys, F. [Ministry of Health and Social Affairs, Brusses, Belgium > Institute of Healt and Epidemiology > > >]
De Plaen, P. [Ministry of Health and Social Affairs, Brusses, Belgium > Institute of Health and Epidemiology > > >]
Ducoffre, G. [Ministry of Health and Social Affairs, Brusses, Belgium > Institute of Health and Epidemiology > > >]
Fagard, R. [Katholieke Universiteit Leuven - KUL > Physiopathology > Hypertension and Cardiovascular Rehabilitation Unit > >]
Lauwerys, R. R. [Université Catholique de Louvain - UCL > Industrial Toxicology and Occupational Mediine Unit > > >]
Lijnen, P. [Katholieke Universiteit Leuven - KUL > Physiopathology > Hypertension and Cardiovascular Rehabilitation Unit > >]
Nick, L. [Ministry of Health and Social Affairs, Brusses, Belgium > Institute of Health and Epidemiology > > >]
Saint-Remy, Annie mailto [Université de Liège - ULg > Département des sciences cliniques > Néphrologie >]
Roels, H. [Université Catholique de Louvain - UCL > Industrial Toxicology and Occupational Medicine Unit > > >]
Rondia, D. [Université de Liège - ULg > Environmental Toxicology Unit > > >]
Sartor, F. [Université de Liège - ULg > Environmental Toxicology Unit > > >]
Thijs, L. [Katholieke Universiteit Leuven - KUL > Physiopathology > Hypertension and Cardiovascular Rehabilitation Unit > >]
1991
American Journal of Epidemiology
Oxford University Press
134
3
257-267
Yes (verified by ORBi)
International
0002-9262
1476-6256
Cary
NC
[en] blood pressure ; cadmium ; cardiovascular diseases ; coronary disease ; hypertension ; lead
[en] In a population study conducted from 1985 to 1989 in Belgium, the authors investigated whether exposure to cadmium is associated with blood pressure elevation and with an increased prevalence of cardiovascular diseases. The participants, aged 20-88 years, constituted a random sample of the households living in two low exposure areas (n = 803) and two high exposure areas (n = 1,283). For each exposure level, a rural and an urban district were selected. The cadmium levels in blood (8.5 vs. 11.0 nmol/liter) and urine (7.2 vs. 8.7 nmol/24 hours) were significantly (p less than 0.001) raised in the two high exposure areas compared with the two low exposure areas (p less than 0.001). Systolic pressure was similar in both rural areas, but in the urban area with high exposure systolic pressure was 5 mmHg (p less than 0.001) higher than in the control town. Diastolic pressure was similar in the four districts and the same was true for the prevalence of hypertension and of other cardiovascular diseases. Adjustment of systolic pressure for blood and urinary cadmium did not remove the difference in systolic pressure between both urban areas, suggesting that it was not related to the cadmium burden on the environment. Further analyses in individual subjects showed that neither blood pressure nor the presence of cardiovascular diseases were significantly and positively correlated with blood and urinary cadmium. Thus, the present population study did not confirm the hypothesis that increased exposure of the population to cadmium is associated with blood pressure elevation and with a higher prevalence of cardiovascular diseases.
Professionals
http://hdl.handle.net/2268/77267

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