ORBi: Block Sébastien - Diterpenes from the leaves of Croton Zambesicus

Reference : Diterpenes from the leaves of Croton Zambesicus


	Document type :	Scientific journals : Article
	Discipline(s) :	Life sciences : Multidisciplinary, general & others
	To cite this reference:	http://hdl.handle.net/2268/77252

Title :	Diterpenes from the leaves of Croton Zambesicus
Language :	English
Author, co-author :	Block, Sébastien [Université Catholique de Louvain (UCL) > Laboratoire de Pharmacognosie > Unité CHAM >]
	Baccelli, Chiara [Université Catholique de Louvain (UCL) > Laboratoire de Pharmacognosie > Unité CHAM >]
	Tinant, Bernard [Université Catholique de Louvain (UCL) > Département de Chimie > Unité CSTR >]
	Van Meervelt, Luc [Katholieke Universiteit Leuven (KUL) > Biomolecular Architecture, Chemistry Department >]
	Rozenberg, Raoul [Université Catholique de Louvain (UCL) > Laboratoire de Spectrométrie de Masse >]
	Habib Jiwan, Jean-Louis [Université Catholique de Louvain (UCL) > Laboratoire de Spectrométrie de Masse >]
	Llabres, Gabriel [Université de Liège - ULg > Département de physique > Département de physique >]
	Gillet, Marie-Claire [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Histologie - Cytologie - Département des sciences biomédicales et précliniques >]
	Quetin-Leclercq, Joëlle [Université Catholique de Louvain (UCL) > Laboratoire de Pharmacognosie > Unité CHAM >]
Publication date :	17-Feb-2004
Journal title :	Phytochemistry
Publisher :	Pergamon Press
Volume :	65
Pages :	1165-1171
Peer reviewed :	Yes (verified by ORBi)
Audience :	International
ISSN :	0031-9422
City :	New York
Country :	NY
Keywords :	[en] Trachylobane ; Croton Zambesicus ; diterpene ; euphorbiaceae ; Pimarane ; Cytotoxicity
Abstract :	[en] Two new trachylobane- and one isopimarane-type diterpenoids: ent-18-hydroxy-trachyloban-3-one; ent-trachyloban-3-one; isopimara-7,15-dien-3b-ol, were isolated from the leaves of Croton zambesicus, together with trans-phytol, b-sitosterol, a-amyrin and stigmasterol. The structures were determined by extensive NMR techniques and X-ray analysis. The cytotoxicity of these compounds has been evaluated on cancer and non-cancer cell-lines.
Target :	Researchers
Permalink :	http://hdl.handle.net/2268/77252
DOI :	10.1016/j.phytochem.2004.02.023

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