ORBi: Lahmouzi Jamila - Effect of nicotine on rat gingival fibroblasts in vitro

Reference : Effect of nicotine on rat gingival fibroblasts in vitro


	Document type :	Scientific journals : Article
	Discipline(s) :	Life sciences : Anatomy (cytology, histology, embryology...) & physiology
	To cite this reference:	http://hdl.handle.net/2268/77096

Title :	Effect of nicotine on rat gingival fibroblasts in vitro
Language :	English
Author, co-author :	Lahmouzi, Jamila [Centre Hospitalier Universitaire de Liège - CHU > > Médecine dentaire >]
	Simain-Sato, Franklin [Centre Hospitalier Universitaire de Liège - CHU > > Médecine dentaire >]
	Defresne, Marie-Paule [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Histologie - Cytologie >]
	Gillet, Marie-Claire [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Histologie - Cytologie - Département des sciences biomédicales et précliniques >]
	Heinen, Ernst [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Histologie humaine >]
	Grisar, Thierry [Centre Hospitalier Universitaire de Liège - CHU > > Neurologie Sart Tilman >]
	Legros, Jean-Jacques [Université de Liège - ULg > Département des sciences cliniques > Département des sciences cliniques >]
	Legrand, Roman [Université de Liège - ULg > Services généraux (Faculté de médecine) > Relations académiques et scientifiques (Médecine) >]
Publication date :	2000
Journal title :	Connective Tissue Research
Publisher :	Taylor & Francis
Volume :	41
Issue/season :	1
Pages :	69-80
Audience :	International
ISSN :	0300-8207
e-ISSN :	1607-8438
City :	Philadelphia
Country :	PA
Keywords :	[en] cell culture ; gingival fibroblasts ; nicotine
Abstract :	[en] Nicotine from 3 to 5 mM affects growth and survival rate of rat gingival fibroblasts in vitro. Ultrastructural analysis revealed dilated mitochondria and vacuolization in treated cells, suggestive of necrosis, but increased apoptosis was also revealed by cytometry. On the basis of this in vitro study, it appear that tobacco, through its component nicotine, may directly affect various functions of rat gingival fibroblasts
Target :	Researchers
Permalink :	http://hdl.handle.net/2268/77096
	also: http://hdl.handle.net/2268/23175

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