Article (Scientific journals)
Effects of Target-Controlled Anesthesia with Propofol and Sufentanil on the Hemodynamic Response to Mayfield Head Holder Application
Hans, Pol; Coussaert, E.; Cantraine, F. et al.
1998In Acta Anaesthesiologica Belgica, 49 (1), p. 7-11
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Abstract :
[en] The effects of target-controlled anesthesia with propofol and sufentanil on the hemodynamic response to Mayfield head holder (MH) application were evaluated in 18 ASA I and II patients undergoing scheduled intracranial surgery. Premedication consisted of hydroxyzine, alprazolam and atropine given orally 1 h before surgery. Anesthesia was provided with propofol and sufentanil using a target-controlled infusion device; constant calculated plasma concentrations of 4 micrograms ml-1 propofol and 0.5 ng ml-1 sufentanil were maintained throughout the study. Muscle relaxation was obtained with atracurium and ventilation was controlled with air/oxygen. The MH was fixed 45 +/- 12 min (mean +/- SD) after induction of anesthesia. Heart rate and systolic, diastolic, and mean non invasive arterial pressure were monitored and recorded 5 min before induction of anesthesia (control), 1 min before MH application (MH-1), at MH application, and 1 and 2 min after MH application. Systolic, diastolic, mean arterial pressure, and heart rate increased significantly during and after MH application when compared with MH-1 values, but remained constantly lower than control. Hemodynamic parameters measured 1 min before MH application were significantly lower than control. The results of the study indicate that target-controlled anesthesia maintained with constant calculated plasma concentrations of 4 micrograms ml-1 propofol and 0.5 ng ml-1 sufentanil prevents the increase in arterial pressure and heart rate beyond control values following MH application but may induce some degree of arterial hypotension in the absence of nociceptive stimulation.
Disciplines :
Anesthesia & intensive care
Author, co-author :
Hans, Pol ;  Université de Liège - ULiège > Département des sciences cliniques > Anesthésie et réanimation
Coussaert, E.
Cantraine, F.
DEWANDRE, Pierre-Yves  ;  Centre Hospitalier Universitaire de Liège - CHU > Département d'Anesthésie et réanimation > Service d'anesthésie - réanimation
Brichant, Jean-François ;  Université de Liège - ULiège > Département des sciences cliniques > Anesthésie et réanimation
Grevesse, M.
Lamy, Maurice ;  Université de Liège - ULiège > Département des sciences cliniques > Anesthésie et réanimation
Language :
English
Title :
Effects of Target-Controlled Anesthesia with Propofol and Sufentanil on the Hemodynamic Response to Mayfield Head Holder Application
Publication date :
1998
Journal title :
Acta Anaesthesiologica Belgica
ISSN :
0001-5164
eISSN :
2736-5239
Publisher :
Acta Medica Belgica, Bruxelles, Belgium
Volume :
49
Issue :
1
Pages :
7-11
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 29 October 2008

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