ORBi: Muylkens Benoît - Bovine herpesvirus 1 infection and infectious bovine rhinotracheitis

Reference : Bovine herpesvirus 1 infection and infectious bovine rhinotracheitis


	Document type :	Scientific journals : Letter to the editor
	Discipline(s) :	Life sciences : Veterinary medicine & animal health
	To cite this reference:	http://hdl.handle.net/2268/7591

Title :	Bovine herpesvirus 1 infection and infectious bovine rhinotracheitis
Language :	English
Author, co-author :	Muylkens, Benoît [Université de Liège - ULg > Département des maladies infectieuses et parasitaires > Virologie, épidémiologie et pathologie des maladies virales >]
	Thiry, Julien [Université de Liège - ULg > Département des maladies infectieuses et parasitaires > Virologie, épidémiologie et pathologie des maladies virales >]
	Kirten, P. [> > > >]
	Schynts, F. [> > > >]
	Thiry, Etienne [Université de Liège - ULg > Département des maladies infectieuses et parasitaires > Virologie, épidémiologie et pathologie des maladies virales >]
Publication date :	2007
Journal title :	Veterinary Research
Publisher :	Edp Sciences S A
Volume :	38
Issue/season :	2
Pages :	181-209
Audience :	International
ISSN :	0928-4249
City :	Les Ulis Cedex A
Keywords :	[en] alphaherpesvirus ; bovine ; infectious bovine rhinotracheitis ; latency ; marker vaccine
Abstract :	[en] Bovine herpesvirus 1 (BoHV-1), classified as an alphaherpesvirus, is a major pathogen of cattle. Primary infection is accompanied by various clinical manifestations such as infectious bovine rhinotracheitis, abortion, infectious pustular vulvovaginitis, and systemic infection in neonates. When animals survive, a life-long latent infection is established in nervous sensory ganglia. Several reactivation stimuli can lead to viral re-excretion, which is responsible for the maintenance of BoHV-1 within a cattle herd. This paper focuses on an updated pathogenesis based on a molecular characterization of BoHV-1 and the description of the virus cycle. Special emphasis is accorded to the impact of the latency and reactivation cycle on the epidemiology and the control of BoHV-1. Several European countries have initiated BoHV-1 eradication schemes because of the significant losses incurred by disease and trading restrictions. The vaccines used against BoHV-1 are described in this context where the differentiation of infected from vaccinated animals is of critical importance to achieve BoHV-1 eradication.
Permalink :	http://hdl.handle.net/2268/7591
DOI :	10.1051/vetres:2006059

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