[en] Through an example, the way to apply Design of Experiments and the Bayesian modeling to develop robust optimal ligand-binding assays (LBA) will be presented. The objectives of a LBA will be re-examined and response of interest derived (precision profile). The concept of Design Space specific for LBA will be introduced in relation with validation, routine and transfer
Research center :
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège
Disciplines :
Mathematics
Author, co-author :
Lebrun, Pierre ; Université de Liège - ULiège > Département de pharmacie > Chimie analytique
Boulanger, Bruno ; Université de Liège - ULiège > Département de pharmacie > Analyse des médicaments
Hubert, Philippe ; Université de Liège - ULiège > Département de pharmacie > Chimie analytique
Language :
English
Title :
How can QbD be used and implemented to optimize method development and validation?
Publication date :
04 November 2010
Event name :
Biological Assay Conference (Informa)
Event organizer :
Informa life science
Event place :
London, United Kingdom
Event date :
3-4 NOV 2010
By request :
Yes
Audience :
International
Funders :
DGTRE - Région wallonne. Direction générale des Technologies, de la Recherche et de l'Énergie [BE] Arlenda S.A. ULiège - Université de Liège [BE]
