Mixed Phenotype Murine Leukemias

[en] Cell lines were derived from eight individual leukemias induced by X-rays in NFS mice. First typed as null cells (surface immunoglobulin negative, Thy-1 negative), they turned out to have a mixed phenotype with myeloid cytochemical markers, pre-B surface antigens and molecular markers of pro-B lymphocytes. They represent murine models for mixed phenotype (pro-pre-B-myeloid) leukemias.

Disciplines :

Anatomy (cytology, histology, embryology...) & physiology

Author, co-author :

Defresne, Marie-Paule ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Histologie - Cytologie

Borremans, B.

Verhofstede, C.

Peled, A.

Thiry, Albert ; Université de Liège - ULiège > Anatomie pathologique

Greimers, Roland ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques

Robberecht, P.

Nabarra, B.

Verschaeve, L.

Hooghe, R.

Language :

English

Title :

Mixed Phenotype Murine Leukemias

Publication date :

August 1993

Journal title :

Leukemia

ISSN :

0887-6924

eISSN :

1476-5551

Publisher :

Nature Publishing Group, United Kingdom

Volume :

Issue :

Pages :

1253-60

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 15 November 2010

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Bibliography

Holmes KL, Pierce JH, Davidson WF, Morse HC. Murine hematopoietic cells with pre-B or pre-B/myeloid characteristics are generated by in vitro transformation with retroviruses containing fes, ras, abl and src oncogenes. J Exp Med 1986;164:443-457.
Sobol RE, Mick R, Royston I, Davey FR, Ellison RR, Newman R, Cuttner J, Griffin JD, Collins H, Nelson DA. Bloomfield CD. Clinical importance of myeloid antigen expression in adult acute lymphoblastic leukemia. N Engl J Med 1987;316:1111-1117.
Smith FO, Lampkin BC, Versteeg C, Flowers DA, Dinndorf PA, Buckley JD, Woods WG, Hammond GD, Bernstein ID. Expression of lymphoid-associated cell surface antigens by childhood acute myeloid leukemia cells lacks prognostic significance. Blood 1992;79:2415-2422.
Schiff C, Milili M, Bossy D, Tabilio A, Falzetti F, Gabert J, Mannoni P, Fougereau M. λ-like and v-pre-B gene expression: an early B-lineage marker of human leukemias. Blood 1991;78:1516-1525.
Wiersma SR, Ortega J, Sobel E, Weinberg K. Clinical importance of myeloid-antigen expression in acute lymphoblastic leukemia of childhood. N Engl J Med 1991; 324:800-808.
Okabe T, Bauer SR, Kudo A. Pre-B lymphocyte-specific transcriptional control of the mouse v-pre-B gene. Eur J Immunol 1992;22:31-36.
Bauer SR, Kubagawa H, Maclennan I, Melchers F. V-pre-B gene expression in hematopoietic malignancies: a lineage- and stage-restricted marker for B-cell precursor leukemias. Blood 1991;78:1581-1588.
Lieberman M, Hansteen GA, McCune JM, Scott ML, White JH, Weissman IL. Indirect induction of radiation lymphomas in mice. J Exp Med 1987;166:1883-1893.
Sasaki M. Current status of cytogenetic studies in animal tumors with special reference to non-random chromosome changes. Cancer Genet Cytogenet 1982;5:153-172.
Azumi J, Sachs L. Chromosome mapping of genes that control differentiation and malignancy in myeloid leukemic cells. Proc Natl Acad Sci USA 1977;74:253-257.
Hayhoe FGJ, Quaglina D. Haematological cytochemistry. London: Churchill Livirgstone, 1980.
Beckstead JH, Halnerson PS, Ries CA, Bainton DF. Enzyme histochemistry and immunohistochemistry on biopsy specimens of pathologic human bone marrow. Blood 1981;57:1088-1098.
Plum J, Koning F, Leclercq G, Tison B, De Smedt M. Expansion of large granular lymphocytes in IL-2-driven 14-day-old fetal thymocytes in organ culture. J Immunol 1990;144:3710-3717.
Ledbetter JA, Herzenberg LA. Xenogeneic monoclonal antibodies to mouse differentiation antigens. Immunol Rev 1979;47:63-90.
Malek TR, Robb RJ, Shevach EM. Identification and initial characterization of a rat monoclonal antibody reactive with the murine interleukin 2 receptor-ligand complex. Proc Natl Acad Sci USA 1983;80:5694-5698.
Aihara Y, Bühring HJ, Aihar M, Klein J. An attempt to produce pre-T cell hybridomas and to identify their antigens. Eur J Immunol 1986;16:1391-1399.
Palacios R, Samaridis J, Thorpe D, Leu T. Identification and characterization of pro-T lymphocytes and lineage-uncommitted lymphocyte precursors from mice with three novel surface markers. J Exp Med 1990;172:219-230.
Springer T, Galfrè G, Secher DS, Milstein C. Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens. Eur J Immunol 1978;8:539-551.
Holmes KL, Langdon WY, Fredrickson TN, Coffman RL, Hoffman PM, Hartley JW, Morse HC. Analysis of neoplasms induced by Cas-br-m MuLV tumor extracts. J Immunol 1986;137:679.
Johnson P, Greenbaum L, Bottomly K, Trowbridge IS. Identification of the alternatively spliced exons of murine CD45 (T200) required for reactivity with B220 and other T200-restricted antibodies. J Exp Med 1989;169:1179-1184.
Maniatis T, Fritsch EF, Sambrook J. Molecular cloning: a laboratory manual. Cold Spring Harbor: Cold Spring Harbor Laboratory, 1982.
Yoshida N, Radbruch A, Rajewsky K. Ig gene rearrangement and expression in the progeny of B-cell progenitors in the course of clonal expansion in bone marrow cultures. EMBO J 1987;6:2735-2741.
Winter E, Krawinkel U, Radbruch A. Directed Ig class switch recombination in activated murine B cells. EMBO J 1987;6:1663-1671.
Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate phenol chloroform extraction. Anal Biochem 1987;162:156-159.
Murray LJ, Lee R, Martens C. In vivo cytokine gene expression in T cell subsets of the autoimmune MRL/Mp-Ipr/lpr mouse. Eur J Immunol 1990;20:163-170.
Montgomery RA, Dallman MJ. Analysis of cytokine gene expression during fetal thymic ontogeny using the polymerase chain reaction. J Immunol 1991;147:554-560.
Kudo A, Melchers F. A second gene, v pre B in the λ5 locus of the mouse, which appears to be selectively expressed in pre-B lymphocytes. EMBO J 1987;6:2267-2272.
Cauvin A, Buscall L, Gourlet P, De Neef P, Gossen D, Arimura A, Miyata A, Coy DH, Robberecht P, Christophe J. The novel VIP-like hypothalamic polypeptide PACAP interacts with high affinity receptors in the human neuroblastoma cell line NB-OK. Peptides 1990;11:773-777.
Cook WD. Thymocyte subsets transformed by Abselson murine leukemia virus. Mol Cell Biol 1985;5:390-397.
Warters RL. Radiation-induced apoptosis in a murine T-cell hybridoma. Cancer Res 1992;52:883-890.
Neiman PE, Thomas SJ, Loring G. Induction of apoptosis during normal and neoplastic B-cell development in the bursa of Fabricius. Proc Natl Acad Sci USA 1991;88:5857-5861.
Mori N, Takamori Y. The genesis of Thy-1- lymphomas in NFS mice exposed to X-irradiation. Radiat Res 1989; 117:35-46.
Erber WN, Mynheer LC, Mason DY. APAAP labelling of blood and bone marrow samples for phenotyping leukemia. Lancet 1986;1:761-765.
Davey FR, Erber WN, Gatter KC, Mason DY. Immunophenotyping of acute myeloid leukemia by immunoalkaline phosphatase (APAAP) labelling with a panel of antibodies. AM. J. Haemotol. 1987;26:157-166.
Legrand. E, Daculsi R, Bach JF, Duplan JF. Influence of serum thymic factors (FTS) on radiation-induced leukaemogenesis in thymectomized AKR mice. Int J Cancer 1981;28:59-64.
Peled A, Haran-Ghera N. High incidence of B cell lymphomas derived from thymectomized AKR mice expressing TL-4 antigen. J Exp Med 1985;162:1081-1086.
Haegerstrand A, Dalsgaard CJ, Jonzon B, Larsson O, Nilsson J. Calcitonin gene-related peptide stimulates proliferation of human endothelial cells. Proc Natl Acad Sci USA 1990;87:3299-3303.
European CGRP in Subarachnoid Haemorrhage Study Group. Effect of calcitonin-gene-related peptide in patients with-delayed postoperative cerebral ischaemia after aneurysmal subarachnoid haemorrhage. Lancet 1992;339:831-834.
Collins RJ. Verschuer LA, Harmon BV, Prentice RL, Pope JH, Kerr JFR. Spontaneous programmed death (apoptosis) of B-chronic lymphocytic leukeaemia cells following their culture in vitro. Br J Haematol 1989;71: 343-350
Kantor AB. The development and repertoire of B-1 cells (CD5 B cells). Immunol Today 1991;12:389-391.
Nishikawa SI, Hayashi SI, Ogawa M, Kunisada T, Nishikawa S, Sudo T, Nakauchi H, Suda T. Control of cell growth and differentiation during early B-cell development by stromal cell molecules. Cold Spring Harbor Symp Quant Biol 1989;54:171-174.
Saeland S, Duvert V, Pandrau D, Caux C, Durand I, Wrighton N, Wideman J, Lee F, Banchereau J. Interleukin-7 induces the proliferation of normal human B-cell precursors. Blood 1991;78:2229-2238.
Overell RW, Clark L, Lynch D, Jerzy R, Schmierer A, Weisser KE, Namen AE, Goodwin RG. Interleukin-7 retroviruses transform pre-B cells by an autocrine mechanism not evident in Abelson murine leukemia virus transformants. Mol Cell Biol 1991;11:1590-1597.
Touw I, Pouwels K, van Agthoven T, van Gurp R, Budel L, Hoogerbrugge H, Delwel R, Goodwin R, Namen A, Löwenberg B. Interleukin-7 is a growth factor of precursor B and T acute lymphoblastic leukemia. Blood 1990;75:2097-2101.
Digel W, Schmid M, Heil G, Conrad P, Gillis S, Porzsolt F. Human interleukin-7 induces proliferation of neoplastic cells from chronic lymphocytic leukemia and acute leukemias. Blood 1991;78:753-759.
Palacios R, Henson G, Steinmetz M, McKearn JP. Interleukin-3 supports growth of mouse pre-B-cell clones in vitro. Nature 1984;309:126-131.
Xia X, Li L, Choi YS. Human recombinant IL-3 is a growth factor for normal B cells. J Immunol 1992; 148:491-497.
Tohda S, Nara N, Murohashi I, Aoki N. Establishment of an interleukin-3-dependent leukemic cell line from a patient with chronic lymphocytic leukemia in the acute phase. Blood 1991;78:1789-1794.
Touw I, Delwel R, Bolhuis R, van Zanen G, Löwenberg B. Common and pre-B acute lymphoblastic leukemia cells express interleukin-2 reteptors, and interleukin-2 stimulates in vitro colony formation. Blood 1985;66:556-561.
Hara H, Sam M, Maki RA, Wu GE, Paige CJ. Characterization of a 70Z/3 pre-B cell derived macrophage clone. Differential expression of Hox family genes. Int Immunol 1990;2:691-696.
Gishizky ML, Johnson-White J, Witte ON. Efficient transplantation of BCR/ABL induced CML like syndrome in mice. Proc Natl Acad Sci 1993;90:3755-3759.
O'Connor R, Cesano A, Kreider BL, Lange B, Clark SC, Nowell PC, Finan J, Rovera G, Santoli D. Growth factor-dependent differentiation along the myeloid and lymphoid lineages in an immature acute T lymphocytic leukemia. J Immunol 1990;145:3779-3787.