Reference : Tumor Necrosis Factor and Interferon Gamma Inhibit the Development of Radiation-Induced ...
Scientific journals : Article
Life sciences : Anatomy (cytology, histology, embryology...) & physiology
http://hdl.handle.net/2268/75633
Tumor Necrosis Factor and Interferon Gamma Inhibit the Development of Radiation-Induced Thymic Lymphomas in C57bl/Ka Mice
English
Boniver, Jacques mailto [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques]
Humblet, Chantal mailto [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Histologie - Cytologie >]
Defresne, Marie-Paule mailto [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Histologie - Cytologie >]
Aug-1989
Leukemia : Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K
3
8
611-3
Yes (verified by ORBi)
International
0887-6924
[en] Recombinant tumor necrosis factor and/or gamma-interferon were injected into C57BL/Ka mice after completion of a whole body split dose irradiation, which usually induces thymic lymphomas in more than 90% of the animals. The survival and the incidence of thymic lymphomas were significantly reduced in the cytokine-injected irradiated mice. The protective effect was similar to that obtained by grafting normal bone marrow cells after irradiation. The mechanisms of lymphoma inhibition by TNF or IFN-gamma are discussed.
http://hdl.handle.net/2268/75633

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