Reference : Osteochondral plate angiogenesis: A new treatment target in osteoarthritis.
Scientific journals : Article
Human health sciences : Rheumatology
http://hdl.handle.net/2268/75570
Osteochondral plate angiogenesis: A new treatment target in osteoarthritis.
English
Pesesse, Laurence mailto [Université de Liège - ULg > Département des sciences de la motricité > Unité de recherche sur l'os et le cartillage (U.R.O.C.) >]
Sanchez, Christelle mailto [Université de Liège - ULg > Département des sciences de la motricité > Unité de recherche sur l'os et le cartillage (U.R.O.C.) >]
Henrotin, Yves mailto [Université de Liège - ULg > Département des sciences de la motricité > Unité de recherche sur l'os et le cartillage (U.R.O.C.) - Didactique des sciences de la santé - Pathologie générale et physiopathologie >]
2011
Joint Bone Spine
Elsevier Science
78
144-149
Yes (verified by ORBi)
International
1297-319X
1778-7254
Paris
France
[en] Healthy adult joint cartilage contains neither blood vessels nor nerves. Osteoarthritic cartilage, in contrast, may be invaded by blood vessels from the subchondral bone. The mechanisms underlying cartilage angiogenesis in osteoarthritis are unclear but may involve hypertrophic chondrocyte differentiation. Active research is under way to identify the factors involved in cartilage angiogenesis. Here, we discuss the pathophysiological mechanisms of osteoarthritic cartilage angiogenesis based on evidence from a systematic literature review of articles retrieved via PubMed and ISI Web of Knowledge. Our conclusions suggest new research perspectives and treatment options.
http://hdl.handle.net/2268/75570
10.1016/j.jbspin.2010.07.001
Copyright (c) 2010 Societe francaise de rhumatologie. Published by Elsevier SAS. All rights reserved.

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Restricted access
BONSOI3318.pdfPublisher postprint492.36 kBRequest copy

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.