Reference : Relationship between biochemical markers and radiographic scores in the evaluation of...
Scientific journals : Article
Human health sciences : Rheumatology
http://hdl.handle.net/2268/75560
Relationship between biochemical markers and radiographic scores in the evaluation of the osteoarticular status of Warmblood stallions
English
Verwilghen, Denis mailto [Université de Liège - ULg > Département clinique des animaux de compagnie et des équidés > Anesthésiologie gén. et pathologie chirurg. des grds animaux >]
Busoni, Valeria mailto [Université de Liège - ULg > Département clinique des animaux de compagnie et des équidés > Imagerie médicale >]
Gangl, Monika [> > > >]
Franck, Thierry mailto [Université de Liège - ULg > Département clinique des animaux de compagnie et des équidés > Anesthésiologie gén. et pathologie chirurg. des grds animaux >]
Lejeune, Jean-Philippe mailto [Université de Liège - ULg > Département clinique des animaux de compagnie et des équidés > Anesthésiologie gén. et pathologie chirurg. des grds animaux >]
Vander Heyden, Laurent mailto [Université de Liège - ULg > Département clinique des animaux de compagnie et des équidés > Anesthésiologie gén. et pathologie chirurg. des grds animaux >]
Detilleux, Johann mailto [Université de Liège - ULg > Département de productions animales > Génétique quantitative - Thériogenologie des animaux de production >]
Grulke, Sigrid mailto [Université de Liège - ULg > Département clinique des animaux de compagnie et des équidés > Département clinique des animaux de compagnie et des équidés >]
Deberg, Michelle mailto [Université de Liège - ULg > Département des sciences de la motricité > Unité de recherche sur l'os et le cartillage (U.R.O.C.) >]
Henrotin, Yves mailto [Université de Liège - ULg > Département des sciences de la motricité > Unité de recherche sur l'os et le cartillage (U.R.O.C.) - Didactique des sciences de la santé - Pathologie générale et physiopathologie >]
Serteyn, Didier mailto [Université de Liège - ULg > Département clinique des animaux de compagnie et des équidés > Anesthésiologie gén. et pathologie chirurg. des grds animaux >]
2009
Research in Veterinary Science
British Veterinary Association
87
2
319-28
Yes (verified by ORBi)
International
0034-5288
London
United Kingdom
[en] Animals ; Biological Markers/metabolism ; Bone and Bones/metabolism/radiography ; Horse Diseases/metabolism/radiography ; Horses/physiology ; Joint Diseases/metabolism/radiography/veterinary ; Joints/metabolism ; Male ; Osteochondrosis/metabolism/radiography/veterinary ; Radiography/methods/veterinary
[en] Establishing the osteoarticular status of the horse is often performed by means of radiological screening of the animals. Widespread blood sampling could reveal to be an interesting alternative to this procedure which is time consuming and sometimes technically difficult. The aim of this study was to investigate the relationship between the radiological status of the horses and the levels of biochemical markers of cartilage degradation and synovial inflammation. A specific radiological scoring and classification system was therefore developed and applied on 63 stallions presented for studbook admission. Additionally, groups of horses were established according to the occurrence of osteochondrosis, degenerative joint disease and distal interphalangeal joint effusion. Insulin growth factor-I, myeloperoxidases, Coll2-1 and Coll2-1NO(2) were used as blood markers. The combination of the blood parameters did not seem to correlate with the used scoring system. Coll2-1NO(2) levels however tended to increase with poorer radiological class and this could therefore potentially be a useful predictor of the osteoarticular status in the horse. Coll2-1 levels were significantly higher in the degenerative joint disease group. A high percentage of horses with distal interphalangeal joint effusion was present in this study and was associated with decreased IGF-I and increased Coll2-1 levels.
http://hdl.handle.net/2268/75560
also: http://hdl.handle.net/2268/9463 ; http://hdl.handle.net/2268/130070
10.1016/j.rvsc.2009.02.002

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