Reference : Biochemical biomarkers of oxidative collagen damage.
Scientific journals : Article
Human health sciences : Rheumatology
http://hdl.handle.net/2268/75194
Biochemical biomarkers of oxidative collagen damage.
English
Henrotin, Yves mailto [Université de Liège - ULg > Département des sciences de la motricité > Unité de recherche sur l'os et le cartillage (U.R.O.C.) - Didactique des sciences de la santé - Pathologie générale et physiopathologie >]
Deberg, Michelle mailto [Université de Liège - ULg > Département des sciences de la motricité > Unité de recherche sur l'os et le cartillage (U.R.O.C.) >]
Mathy, Marianne [Université de Liège - ULg > Département des sciences de la motricité > Unité de recherche sur l'os et le cartillage (U.R.O.C.) >]
Deby-Dupont, G. [> > > >]
2009
Advances in Clinical Chemistry
Academic Press
49
31-55
Yes (verified by ORBi)
International
0065-2423
New York
NY
[en] Animals ; Biological Markers ; Collagen/chemistry ; Humans ; Oxidative Stress ; Oxygen/chemistry
[en] Collagens are major constituents of connective tissues in the animal kingdom. During aging and inflammatory-related diseases, the collagen network undergoes oxidation that leads to structural and biochemical alterations within the collagen molecule. Collagen oxidation appears to be a key determinant of aging and a critical physiopathologic mechanism of numerous diseases. Further, the detection of oxidized-collagen peptides seems to be a promising approach for the diagnosis and the prognosis of inflammatory diseases. This chapter reviews the structural and biochemical changes to collagen induced by reactive oxygen and nitrogen species and discusses recent data on the use of collagen-derived biomarkers for measuring oxidative damage.
http://hdl.handle.net/2268/75194

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