Article (Scientific journals)
Diversity among Bovine Pestiviruses
Hamers, Claude; Dehan, Pierre; Couvreur, B. et al.
2001In Veterinary Journal, 161 (2), p. 112-22
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Keywords :
Bovine viral; diarrhoea; genotype; diversity; pestivirus
Abstract :
[en] Bovine viral diarrhoea virus (BVDV) isolates are characterized by an important genetic, antigenic and pathogenic diversity. The emergence of new hypervirulent BVDV strains in North America has provided clear evidence of pathogenic differences between BVDV strains. The origin of BVDV diversity is related to high mutation rate occurring in RNA viruses but the consequences of mutations obviously depend on the genes which are involved. Mutations in genes encoding for structural proteins of immunological importance may have practical implications.Knowledge of BVDV diversity is important for understanding the wide variety of pathogenesis of diseases caused by the virus, for monitoring the epidemiology of the different types and for the design of optimum laboratory tests and vaccines.This review focuses on the origin and consequences of BVDV diversity with regard to pathogenesis, biotypes, and antigenic and genetic variations.
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Hamers, Claude ;  Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Département des maladies infectieuses et parasitaires
Dehan, Pierre ;  Université de Liège - ULiège > Immunology and Vaccinology > Infectious Diseases
Couvreur, B.;  Veterinary and Agrochemical Research Centre (VAR) > Virology
Letellier, C.;  Veterinary and Agrochemical Research Centre (VAR) > Virology
Kerkhofs, P.;  Veterinary and Agrochemical Research Centre (VAR) > Virology
Pastoret, Paul-Pierre ;  Université de Liège - ULiège > Immunology and Vaccinology > Infectious Diseases
Language :
English
Title :
Diversity among Bovine Pestiviruses
Publication date :
March 2001
Journal title :
Veterinary Journal
ISSN :
1090-0233
eISSN :
1532-2971
Publisher :
Elsevier
Volume :
161
Issue :
2
Pages :
112-22
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 27 October 2010

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