Reference : Manifestations hemodynamiques et respiratoires de la preeclampsie.
Scientific journals : Article
Human health sciences : Anesthesia & intensive care
Human health sciences : Reproductive medicine (gynecology, andrology, obstetrics)
http://hdl.handle.net/2268/73505
Manifestations hemodynamiques et respiratoires de la preeclampsie.
French
[en] Circulatory and respiratory problems in preeclampsia.
Brichant, Jean-François mailto [Université de Liège - ULg > Département des sciences cliniques > Anesthésie et réanimation >]
Brichant, Géraldine [Université de Liège - ULg > Département des sciences cliniques > Labo de biologie des tumeurs et du développement >]
Dewandre, Pierre-Yves mailto [Centre Hospitalier Universitaire de Liège - CHU > > Anesthésie et réanimation >]
Foidart, Jean-Michel mailto [Université de Liège - ULg > Département des sciences cliniques > Gynécologie - Obstétrique - Labo de biologie des tumeurs et du développement >]
2010
Annales Françaises d'Anesthésie et de Réanimation
Elsevier
29
e91-e95
Yes (verified by ORBi)
International
0750-7658
1769-6623
Paris
France
[en] Haemodynamics and preeclampsia ; Acute pulmonary edema
[en] The hemodynamic and cardiovascular changes seen during PE vary according to the natural history of the disease, its severity and eventual therapeutic measures taken. In the early stages of pregnancy, patients who will eventually develop PE, present with a blood pressure which even though within normal limits, is higher than in other women. Similarly, their cardiac output is higher with a normal or decreased peripheral vascular resistance. As soon as the clinical signs of the disease appear, the hemodynamic picture usually shifts toward that of a high peripheral resistance with low cardiac output. Sometimes however, a clinically hyperkinetic circulation may be demonstrated. In PE patients, cardiac preload pressures are usually normal even though the circulatory volumes are lower by 600 to 800ml when compared to those found in normal pregnancy. The cardiac function is however usually preserved during PE. PE induces an exaggerated capillary permeability. This results in the worsening of the airway edema which may render the intubation very difficult. The increased capillary permeability contributes, among other factors, to the heightened risk of acute pulmonary edema. It is not justified to administer an anti-hypertensive treatment to PE women presenting with only moderate hypertension. An anti-hypertensive treatment must only be initiated whenever the hypertension is severe (i.e. SBP>/=160mmHg and/or DBP>/=110mmHg) in order to reduce the risk of maternal complications. In the absence of objective comparative data assessing anti-hypertensive agents for the PE patient, the choice of therapy relies predominantly on the practitioners' own experience. Systematic circulatory volume expansion has not been proven to improve the maternal nor the neonatal prognosis. Such treatment is to be reserved solely for situations in which correcting a hypo-volemia is absolutely necessary. The treatment of acute pulmonary edema in a PE patient is symptomatic and includes the administration of vasodilating agents and of diuretics. A benefit in setting-up an invasive monitoring of the pulmonary artery occlusive pressure has not been demonstrated. The sonographic surveillance of the hemodynamic state can however be useful in these circumstances.
http://hdl.handle.net/2268/73505
10.1016/j.annfar.2010.02.023
Copyright (c) 2010 Elsevier Masson SAS. All rights reserved.

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