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Article (Scientific journals)
Calcitropic effect of recombinant prolactins in Oreochromis mossambicus
Flik, G.; Rentier-Delrue, Françoise; Wendelaar-Bonga, S. E.
1994In The American Physiological Society, p. 1302-1308
Peer reviewed
 

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Keywords :
Tilapia; chloride cells, mucocytes; cortisol, prolactin
Abstract :
[en] Homologous recombinant tilapia prolactins 1 and 2 were tested for calcitropic activity in tilapia Oreochromis mossambicus. Injection of both PRLs induced hypercalcemia that resulted for an enhanced calcium influx via the gills and a decreased calcium efflux. Both PRLs increased the density of the Ca2+-transporting Ca2+-adenosinetriphosphatase in a plasma membrane preparation of the branchial epithelium. Dose-response studies demonstrated that the PRL-1 was roughly twofold more potent than PRL2 in inducing hypercalcemia, in enhacing basal levels of cortisol and in stimulating opercular ionocyte density. But both PRL were equipotent in stimulating the dermal mucocyte frequency.
Disciplines :
Anatomy (cytology, histology, embryology...) & physiology
Author, co-author :
Flik, G.;  University of Nijmegen > Animal Physiology
Rentier-Delrue, Françoise ;  Université de Liège - ULiège > Biologie et génétique moléculaire
Wendelaar-Bonga, S. E.;  University of Nijmegen > Animal Physiology
Language :
English
Title :
Calcitropic effect of recombinant prolactins in Oreochromis mossambicus
Publication date :
1994
Journal title :
The American Physiological Society
Pages :
R1302-1308
Peer reviewed :
Peer reviewed
Available on ORBi :
since 01 October 2010

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