Reference : The enterotoxin gene (cpe) of Clostridium perfringens can be chromosomal or plasmid-borne
Scientific journals : Article
Life sciences : Microbiology
http://hdl.handle.net/2268/7298
The enterotoxin gene (cpe) of Clostridium perfringens can be chromosomal or plasmid-borne
English
Cornillot, Emmanuel [> >]
Saint-Joanis, Brigitte [> >]
Daube, Georges mailto [Université de Liège - ULg > Département de sciences des denrées alimentaires > Microbiologie des denrées alimentaires >]
Canard, Bruno [> >]
Granum, Per Einar [> >]
Cole, Stewart T. [> >]
1995
Molecular Microbiology
Blackwell Publishing
15
639-647
Yes (verified by ORBi)
International
0950-382X
1365-2958
Oxford
United Kingdom
[en] The location of the cpe gene, encoding the enterotoxin responsible for food poisoning in humans, has been studied in a series of enterotoxigenic Ciostridium perfringens strains by means of pulsed field gel electrophoresis of genomic DNA. The cpe gene was found at the same chromosomal locus in strains associated with food poisoning in humans and was shown to be linked to a repetitive sequence, the Hin dlll repeat, and an open reading frame, ORF3, that may be part of an insertion sequence. In contrast, when the strains originated from domesticated livestock cpe was located on a large episome where it was often close to a copy of the transposable element IS 1151. In these cases, the Hin dlll repeat was not linked to the cpe gene although this was generally preceded by ORF3
Researchers ; Students
http://hdl.handle.net/2268/7298
10.1111/j.1365-2958.1995.tb02373.x

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