Article (Scientific journals)
Effect of intra-operative magnesium sulphate on pain relief and patient comfort after major lumbar orthopaedic surgery
Levaux, Christophe; BONHOMME, Vincent; DEWANDRE, Pierre-Yves et al.
2003In Anaesthesia, 58 (2), p. 131-135
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Keywords :
surgery, orthopaedic, lumbar arthrodesis; analgesia, postoperative; patients, comfort; drugs, opioids, magnesium, piritramide
Abstract :
[en] The effects of intra-operative magnesium sulphate on pain relief after major lumbar surgery were investigated in 24 patients. Patients were randomly allocated to receive either an infusion of 50 mg x kg(-1) magnesium sulphate or an equivalent volume of saline at induction of anaesthesia. Anaesthesia was induced with propofol and remifentanil. Tracheal intubation was facilitated using rocuronium. Maintenance was achieved with remifentanil and sevoflurane in nitrous oxide/ oxygen. Intra-operative monitoring included standard equipment and neuromuscular transmission. During surgery, neuromuscular block recovery was longer in the magnesium group. Postoperative opioid consumption and pain scores were lower in the magnesium group. The first night's sleep and the global satisfaction scores were better in the magnesium group. The results of the study support magnesium sulphate as a useful adjuvant for postoperative analgesia after major lumbar surgery.
Disciplines :
Anesthesia & intensive care
Author, co-author :
Levaux, Christophe
BONHOMME, Vincent  ;  Centre Hospitalier Universitaire de Liège - CHU > Département d'Anesthésie et réanimation > Service d'anesthésie - réanimation
DEWANDRE, Pierre-Yves  ;  Centre Hospitalier Universitaire de Liège - CHU > Département d'Anesthésie et réanimation > Service d'anesthésie - réanimation
BRICHANT, Jean-François ;  Centre Hospitalier Universitaire de Liège - CHU > Département d'Anesthésie et réanimation > Service d'anesthésie - réanimation
HANS, Pol ;  Centre Hospitalier Universitaire de Liège - CHU > Anesthésie et réanimation
Language :
English
Title :
Effect of intra-operative magnesium sulphate on pain relief and patient comfort after major lumbar orthopaedic surgery
Publication date :
February 2003
Journal title :
Anaesthesia
ISSN :
0003-2409
eISSN :
1365-2044
Publisher :
Blackwell Publishing Ltd, Oxford, United Kingdom
Volume :
58
Issue :
2
Pages :
131-135
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 27 October 2008

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