Reference : Protéomique par SELDI-TOF-MS des maladies inflammatoires articulaires: identification...
Scientific journals : Article
Human health sciences : Rheumatology
http://hdl.handle.net/2268/72446
Protéomique par SELDI-TOF-MS des maladies inflammatoires articulaires: identification des protéines S100 comme protéines d'intérêt
French
[en] Proteomics studies on arthritis by SELDI-TOF-MS: identification of the S100 proteins family as proteins of interest
De Seny, Dominique [Université de Liège - ULg > > Rhumatologie >]
Ribbens, Clio [Université de Liège - ULg > > Rhumatologie >]
Cobraiville, Gaël [Université de Liège - ULg > > Rhumatologie - Chimie médicale >]
Meuwis, Marie-Alice [Université de Liège - ULg > > GIGA-Management : Plate-forme protéomique >]
Marée, Raphaël [Université de Liège - ULg > > GIGA-Management : Plateforme bioinformatique >]
Geurts, Pierre [Université de Liège - ULg > Dép. d'électric., électron. et informat. (Inst.Montefiore) > Systèmes et modélisation >]
Wehenkel, Louis [Université de Liège - ULg > Dép. d'électric., électron. et informat. (Inst.Montefiore) > Systèmes et modélisation >]
Louis, Edouard mailto [Université de Liège - ULg > Département des sciences cliniques > Hépato-gastroentérologie >]
Merville, Marie-Paule [Université de Liège - ULg > Département de pharmacie > Chimie médicale >]
Fillet, Marianne [Université de Liège - ULg > Département de pharmacie > Analyse des médicaments >]
Malaise, Michel [Université de Liège - ULg > Département des sciences cliniques > Rhumatologie >]
2009
Revue Médicale de Liège
Hopital de Baviere
64
Spec No
29-35
Yes (verified by ORBi)
National
0370-629X
Liège
Belgique
[en] proteomics ; biomarkers ; SELDI-TOF-MS
[en] Clinical proteomics is a technical approach studying the entire proteome
expressed by cells, tissues or organs. It describes the dynamics of cell
regulation by detecting molecular events related to diseases development.
Proteomic techniques focus mainly on identification of new biomarkers or new
therapeutic targets. It is a multidisciplinary approach using medical,
biological, bioanalytical and bioinformatics knowledges. A strong collaboration
between these fields allowed SELDI-TOF-MS proteomics studies to be performed at
the CHU and the University of Liege, in GIGA-Research facilities. The aim of
these studies was driven along three main axes of research related to the
identification of biomarkers specific to a studied pathology, to a common
biological pathway and, finally, to a treatment response.
Researchers ; Professionals ; Students ; General public
http://hdl.handle.net/2268/72446
http://www.rmlg.ulg.ac.be
This work was presented in the setting of the "Synthese CHU 2009" meeting.

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