Reference : Potentialités antipaludiques des alcaloïdes indoliques
Scientific journals : Article
Human health sciences : Pharmacy, pharmacology & toxicology
Potentialités antipaludiques des alcaloïdes indoliques
[en] Potential antimalarial activity of indole alkaloids
Frederich, Michel mailto [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
Philippe, Geneviève mailto [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
Tits, Monique mailto [Université de Liège - ULg > Département de pharmacie > Phytochimie et phytothérapie >]
Angenot, Luc mailto [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
Actualités de Chimie Thérapeutique
Société de Chimie Thérapeutique
[en] Indole alkaloids ; antimalarial activity
[en] This paper will be mainly illustrated with references to selected antiplasmodial compounds:- indole alkaloid analogues of emetine isolated from Strychnos usambarensis and Pogonopus tubulosus-other bisindole alkaloids isolated from Loganiacea and Apocynaceae -indoloquinolines (cryptolepine and analogues) -indolo quinazoline-6,12-diones and derivatives from Strobilanthes and other sources -aminopolycyclic beta-carbolines ( manzamines) !solated from Indo-Pacific sponges. The paper will be finally also focused on the design of chemosensitizers that are capable of reversing in vitro chloroquine resistance( case of some mono-indole alkaloids).
Researchers ; Professionals
Paper of a lecture presented by one of us (L.A.) at the 42nd International meeting on Medicinal Chemistry that has been hold at Marseilles ( France) in July 2006.

File(s) associated to this reference

Fulltext file(s):

Restricted access
Actualites de chimie therapeutique 2007.pdfAuthor preprint4.81 MBRequest copy

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.