Reference : Preconditioning and protection against ischaemia-reperfusion in non-cardiac organs: a pl...
Scientific journals : Letter to the editor
Human health sciences : Anesthesia & intensive care
http://hdl.handle.net/2268/7175
Preconditioning and protection against ischaemia-reperfusion in non-cardiac organs: a place for volatile anaesthetics?
English
Minguet, Grégory mailto [Centre Hospitalier Universitaire de Liège - CHU > > Anesthésie et réanimation >]
Joris, Jean [Université de Liège - ULg > Département des sciences cliniques > Anesthésie et réanimation]
Lamy, Maurice mailto [Université de Liège - ULg > Département des sciences cliniques > Anesthésie et réanimation]
Sep-2007
European Journal of Anaesthesiology
Cambridge University Press
24
9
733-745
Yes (verified by ORBi)
International
0265-0215
1365-2346
Cambridge
United Kingdom
[en] anaesthesia ; anaesthetics inhalation ; ischaemia-reperfusion ; mitochondria ; ischaemic preconditioning
[en] There is an increasing body of evidence that volatile anaesthetics protect myocardium against ischaemic insult by a mechanism termed 'anaesthetic preconditioning'. Anaesthetic preconditioning and ischaemic preconditioning share several common mechanisms of action. Since ischaemic preconditioning has been demonstrated in organs other than the heart, anaesthetic preconditioning might also apply in these organs and have significant clinical applications in surgical procedures carrying a high risk of ischaemia-reperfusion injury. After a brief review on myocardial preconditioning, experimental and clinical data on preconditioning in non-cardiac tissues will be presented. Potential benefits of anaesthetic preconditioning during non-cardiac surgery will be addressed.
http://hdl.handle.net/2268/7175
10.1017/S0265021507000531

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