Reference : FDC-B1: a new monoclonal antibody directed against bovine follicular dendritic cells
Scientific journals : Article
Life sciences : Anatomy (cytology, histology, embryology...) & physiology
Life sciences : Veterinary medicine & animal health
http://hdl.handle.net/2268/7131
FDC-B1: a new monoclonal antibody directed against bovine follicular dendritic cells
English
Defaweux, Valérie mailto [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Histologie humaine >]
Mélot, France [Université de Liège - ULg > Services généraux (Faculté de médecine) > Service administratif de la Faculté (Médecine) >]
Jolois, Olivier mailto [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Histologie humaine >]
Collard, A. [> >]
Robert, B. [> >]
Heinen, Ernst [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Histologie humaine >]
Antoine, Nadine [Université de Liège - ULg > Département de morphologie et pathologie > Histologie >]
Jan-2004
Veterinary Immunology and Immunopathology
Elsevier Science Bv
97
1-2
1-9
Yes (verified by ORBi)
International
0165-2427
Amsterdam
[en] follicular dendritic cells ; anti-FDC antibodies ; prions
[en] Follicular dendritic cells (FDCs) are a unique population of accessory cells located in the light zone of the germinal centres of lymphoid follicles. Their involvement in the generation of Immoral immune responses implies a potential role for these cells in many disorders. Indeed, in prion diseases, FDCs seem to be the major sites of extraneuronal cellular prion protein expression and the principal sites of the infectious agent accumulation in lymphoid organs. The identification of FDC is useful for the analysis of their distribution in reactive lymphoid tissue as well as in pathological conditions. The production and characterisation of a new mouse monoclonal antibody directed against bovine follicular dendritic cells (FDC-B1) is reported. The antigen detected by FDC-B1 is expressed exclusively on the surface of FDCs in ruminant lymphoid organs. The antigen has an approximate molecular weight of 28 kDa. (C) 2003 Elsevier B.V. All rights reserved.
http://hdl.handle.net/2268/7131
France Mélot et Valérie Defaweux sont toutes les deux co-auteurs de ce papiers

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