Reference : Biomolecules in multilayer film for antimicrobial and easy-cleaning stainless steel s...
Scientific journals : Article
Life sciences : Biochemistry, biophysics & molecular biology
Engineering, computing & technology : Materials science & engineering
http://hdl.handle.net/2268/71035
Biomolecules in multilayer film for antimicrobial and easy-cleaning stainless steel surface applications
English
Vreuls, Christelle mailto [Université de Liège - ULg > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire >]
Zocchi, Germaine mailto [Université de Liège - ULg > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire >]
Garitte, Geoffrey mailto [Université de Liège - ULg > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire >]
Archambeau, Catherine [ArcelorMittal Research Liège > New coating technologies > > >]
Martial, Joseph mailto [Université de Liège - ULg > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire >]
Van de Weerdt, Cécile mailto [Université de Liège - ULg > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire >]
2010
Biofouling
Taylor & Francis
26
6
645-656
Yes (verified by ORBi)
International
0892-7014
1029-2454
London
United Kingdom
[en] Microorganisms are able to attach to, grow on, and ultimately form biofilms on a large variety of surfaces, such as industrial equipment, food contact surfaces, medical implants, prostheses and operating rooms. Once organized into biofilms, bacteria are difficult to remove and kill, which increases the risk of cross-contamination and infection. One way to address the problem may thus be to develop antibacterial, anti-adhesion, ‘easy cleaning’ surfaces. In this study, stainless steel (SS) surfaces with antibacterial properties were created by embedding several antimicrobial peptides in a multilayer film architecture. The biocidal effect of these surfaces was demonstrated against both Gram-positive and Gram-negative bacteria according to two ISO tests. Also, coating SS surfaces with either mucin or heparin led to a reduction of <i>S. epidermidis</i> adhesion of almost 95% <i>vs</i> the bare substratum. Finally, by combining both antibacterial and anti-adhesion biomolecules in the same multilayer film, SS surfaces with better cleanability were produced. This surface coating property may help to delay the buildup of a dead bacterial layer which is known to progressively reduce exposure of the coating, leading to an undesirable decrease in the antibacterial effect of the surface.
Giga-Systems Biology and Chemical Biology ; ArcelorMittal Research Liège ; Center for Education and Research on Macromolecules (CERM)
Région wallonne : Direction générale des Technologies, de la Recherche et de l'Energie - DGTRE
Biocoat
http://hdl.handle.net/2268/71035

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