Unpublished conference/Abstract (Scientific congresses and symposiums)
Equivalent mixed model for joint genetic evaluation considering molecular and phenotypic information
Gengler, Nicolas; Colinet, Frédéric
2009ADSA - CSAS - ASAS Joint Annual Meeting 2009
 

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Keywords :
molecular information; joint estimation; genomic selection
Abstract :
[en] Currently efforts are underway to introduce molecular information into genetic evaluation systems. A particular situation is genomic selection however simpler cases exists where major genes are known and used by breeders. A new alternative strategy for the prediction of gene effects and especially their smooth integration into genetic evaluations based on an equivalent method was developed from existing theory. Underlying hypothesis were based on the idea that knowledge of genotypes will not affect overall additive genetic variance but only change expected values of genetic effects for animals with known genotypes. The developed equations were modified to allow that not all animals were genotyped. As the underlying mixed model is open a very large range of models can be used in situations including random regression models, multipletrait, maternal effects and multiple-across-country-evaluation models. Computations involved successive solving of two mixed models, with the use of an linear extrapolation to speed up convergence of gene effects. The method was tested for several known major genes and QTL, e.g. for the mh gene in the dual-purpose Belgian Blue population in Belgium. Modifications of the method could also be developed to be useful in the context of genomic selection.
Disciplines :
Genetics & genetic processes
Animal production & animal husbandry
Author, co-author :
Gengler, Nicolas  ;  Université de Liège - ULiège > Sciences agronomiques > Zootechnie
Colinet, Frédéric ;  Université de Liège - ULiège > Sciences agronomiques > Zootechnie
Language :
English
Title :
Equivalent mixed model for joint genetic evaluation considering molecular and phenotypic information
Publication date :
July 2009
Event name :
ADSA - CSAS - ASAS Joint Annual Meeting 2009
Event organizer :
Federation of Animal Science Societies
Event place :
Montréal, Québec, Canada
Event date :
du 12 au 16 Juillet 2009
Audience :
International
Available on ORBi :
since 16 August 2010

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