Letter to the editor (Scientific journals)
Factors promoting rupture of abdominal aortic aneurysms
Van Damme, Hendrik; Sakalihasan, Natzi; Limet, Raymond
2005In Acta Chirurgica Belgica, 105 (1), p. 1-12
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Keywords :
aneurysm, abdominal aorta; aneurysm, rupture; matrix metalloproteinases; aneurysm, thrombus; finite element analysis; mechanical stress
Abstract :
[en] The risk for rupture of an abdominal aortic aneurysm is widely believed to be related to its maximum diameter. Rupture occurs at the site of maximum wall stress, when it exceeds the tensile strength of the aortic wall. Basic research confirmed that peak wall stress and aortic wall biodegradation contribute to the mechanism of aneurysm rupture. In order to highlight the role of loss in wall strength and increase in focal peak stress, the authors reviewed recent literature. The clinical relevance of these recent insights in the etiopathogenesis of aneurysm rupture is analysed.
Disciplines :
Surgery
Author, co-author :
Van Damme, Hendrik ;  Université de Liège - ULiège > Département des sciences cliniques > Département des sciences cliniques
Sakalihasan, Natzi 
Limet, Raymond ;  Université de Liège - ULiège > Département des sciences cliniques > Chirurgie cardio-vasculaire et thoracique
Language :
English
Title :
Factors promoting rupture of abdominal aortic aneurysms
Publication date :
February 2005
Journal title :
Acta Chirurgica Belgica
ISSN :
1784-3421
eISSN :
2577-0160
Publisher :
Acta Medical Belgica, Brussels, Belgium
Volume :
105
Issue :
1
Pages :
1-12
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 25 February 2011

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