Reference : Successful Treatment of Pulmonary Lymphangioleiomyomatosis with Progestins: A Case Report
Scientific journals : Article
Human health sciences : Reproductive medicine (gynecology, andrology, obstetrics)
http://hdl.handle.net/2268/67679
Successful Treatment of Pulmonary Lymphangioleiomyomatosis with Progestins: A Case Report
English
Denoo, Xavier [Centre Hospitalier Universitaire de Liège - CHU > > Gynécologie-Obstétrique CHR >]
Hermans, Gilberte [Centre Hospitalier Universitaire de Liège - CHU > > Anatomie pathologique >]
Degives, R. [ > > ]
Foidart, Jean-Michel mailto [Université de Liège - ULg > Département des sciences cliniques > Gynécologie - Obstétrique - Labo de biologie des tumeurs et du développement >]
Jan-1999
CHEST
American College of Chest Physicians
115
1
276-9
Yes (verified by ORBi)
International
0012-3692
1931-3543
Northbrook
IL
[en] The diagnostic approach, clinical evolution, and treatment of a patient with primary pulmonary lymphangioleiomyomatosis are reported. This patient presented a restrictive respiratory syndrome resistant to conventional glucocorticoid therapy. The diagnosis, based on clinical and histologic examinations, was confirmed by immunohistochemical localization of one of the desmins, the smooth muscle cell actin, and HMB45 antigen. The patient received treatment with an anti-estrogenic agent (tamoxifen citrate) and high doses of medroxyprogesterone acetate, an antigonadotropic progestin. Respiratory function improved rapidly with clinical relief.
http://hdl.handle.net/2268/67679
10.1378/chest.115.1.276

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