Reference : Vitamin D and musculoskeletal health, cardiovascular disease, autoimmunity and cancer: R...
Scientific journals : Article
Human health sciences : Oncology
Human health sciences : Immunology & infectious disease
Human health sciences : General & internal medicine
Human health sciences : Endocrinology, metabolism & nutrition
http://hdl.handle.net/2268/65751
Vitamin D and musculoskeletal health, cardiovascular disease, autoimmunity and cancer: Recommendations for clinical practice.
English
Souberbielle, J. C. [> > > >]
Body, J. J. [> > > >]
Lappe, J. M. [> > > >]
Plebani, M. [> > > >]
Shoenfeld, Y. [> > > >]
Wang, T. J. [> > > >]
Bischoff-Ferrari, H. A. [> > > >]
Cavalier, Etienne mailto [Centre Hospitalier Universitaire de Liège - CHU > > Chimie médicale >]
Ebeling, P. R. [> > > >]
Fardellone, P. [> > > >]
Gandini, S. [> > > >]
Gruson, D. [> > > >]
Guerin, A. P. [> > > >]
Heickendorff, L. [> > > >]
Hollis, B. W. [> > > >]
Ish-Shalom, S. [> > > >]
Jean, Guillaume [> >]
von Landenberg, P. [> > > >]
Largura, A. [> > > >]
Olsson, T. [> > > >]
Pierrot-Deseilligny, C. [> > > >]
Pilz, S. [> > > >]
Tincani, A. [> > > >]
Valcour, A. [> > > >]
Zittermann, A. [> > > >]
Sep-2010
Autoimmunity Reviews
Elsevier Science
9
11
709-15
Yes (verified by ORBi)
International
1568-9972
Amsterdam
The Netherlands
[en] BACKGROUND: There is increasing evidence that, in addition to the well-known effects on musculoskeletal health, vitamin D status may be related to a number of non-skeletal diseases. An international expert panel formulated recommendations on vitamin D for clinical practice, taking into consideration the best evidence available based on published literature today. In addition, where data were limited to smaller clinical trials or epidemiologic studies, the panel made expert-opinion based recommendations. METHODS: Twenty-five experts from various disciplines (classical clinical applications, cardiology, autoimmunity, and cancer) established draft recommendations during a 2-day meeting. Thereafter, representatives of all disciplines refined the recommendations and related texts, subsequently reviewed by all panelists. For all recommendations, panelists expressed the extent of agreement using a 5-point scale. RESULTS AND CONCLUSION: Recommendations were restricted to clinical practice and concern adult patients with or at risk for fractures, falls, cardiovascular or autoimmune diseases, and cancer. The panel reached substantial agreement about the need for vitamin D supplementation in specific groups of patients in these clinical areas and the need for assessing their 25-hydroxyvitamin D (25(OH)D) serum levels for optimal clinical care. A target range of at least 30 to 40 ng/mL was recommended. As response to treatment varies by environmental factors and starting levels of 25(OH)D, testing may be warranted after at least 3 months of supplementation. An assay measuring both 25(OH)D(2) and 25(OH)D(3) is recommended. Dark-skinned or veiled individuals not exposed much to the sun, elderly and institutionalized individuals may be supplemented (800 IU/day) without baseline testing.
http://hdl.handle.net/2268/65751
10.1016/j.autrev.2010.06.009
Copyright (c) 2010 Elsevier B.V. All rights reserved.

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