Article (Scientific journals)
Pulmonary function changes induced by experimental dichlorvos toxicosis in calves
Lekeux, Pierre; Kyavu, A.; Clercx, Cécile et al.
1986In Research in Veterinary Science, 40 (3), p. 318-321
Peer Reviewed verified by ORBi
 

Files


Full Text
LekeuxP_ResVetSci_1986.pdf
Publisher postprint (1.02 MB)
Request a copy

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
Pulmonary Function; calves
Abstract :
[en] Clinical and pulmonary function changes induced by intravenous dichlorvos (2,2-dichlorvinyldimethyl phosphate) (DDVP) toxicosis, and reversibility of these changes after atropine treatment were investigated in six Friesian calves one to three months old. From one minute after dosage, all animals showed severe respiratory distress, excitation, weakness, muscle fasciculation and cholinesterase inhibition. Decrease in dynamic lung compliance and arterial oxygen tension and increase in total pulmonary resistance, viscous work of breathing and alveolar arterial oxygen gradient were highly significant (P less than 0.01). On the other hand, body secretions, heart rate, respiratory rate, tidal volume and arterial carbon dioxide tension were not significantly affected by DDVP injection. Atropine promptly and completely reversed these changes, except for muscle fasciculations, central depression and cholinesterase inhibition which disappeared progressively within 24 hours.
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Lekeux, Pierre ;  Université de Liège - ULiège > Faculté de Médecine vétérinaire
Kyavu, A.;  Université de Liège - ULiège > Faculté de Médecine vétérinaire
Clercx, Cécile  ;  Université de Liège - ULiège > Faculté de Médecine vétérinaire
Ansay, Michel ;  Université de Liège - ULiège > Faculté de médecine vétérinaire
Language :
English
Title :
Pulmonary function changes induced by experimental dichlorvos toxicosis in calves
Publication date :
1986
Journal title :
Research in Veterinary Science
ISSN :
0034-5288
eISSN :
1532-2661
Publisher :
British Veterinary Association, London, United Kingdom
Volume :
40
Issue :
3
Pages :
318-321
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 17 February 2009

Statistics


Number of views
85 (7 by ULiège)
Number of downloads
0 (0 by ULiège)

Scopus citations®
 
13
Scopus citations®
without self-citations
8
OpenCitations
 
13

Bibliography


Similar publications



Contact ORBi