Reference : Clinicopathological features of eyelid skin tumors. A retrospective study of 5504 cas...
Scientific journals : Article
Human health sciences : Ophthalmology
Clinicopathological features of eyelid skin tumors. A retrospective study of 5504 cases and review of literature.
Deprez, Manuel [Université de Liège - ULg > Département des sciences cliniques > Neuropathologie >]
Uffer, Sylvie [Hôpital Ophtalmique Jules Gonin, Lausanne, Suisse > Laboratoire d'Ophtalmopathologie > > >]
American Journal of Dermatopathology
Lippincott Williams & Wilkins
Yes (verified by ORBi)
[en] Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biopsy ; Carcinoma, Basal Cell/pathology ; Carcinoma, Squamous Cell/pathology ; Child ; Child, Preschool ; Eyelid Diseases/pathology ; Eyelid Neoplasms/pathology ; Female ; Hidrocystoma/pathology ; Humans ; Infant ; Keratosis, Seborrheic/pathology ; Male ; Middle Aged ; Nevus, Pigmented/pathology ; Papilloma/pathology ; Predictive Value of Tests ; Retrospective Studies ; Sebaceous Gland Neoplasms/pathology ; Skin Neoplasms/pathology ; Sweat Gland Neoplasms/pathology ; Xanthomatosis/pathology ; Young Adult
[en] Eyelid tumors are the most common neoplasm in daily ophthalmology practice and encompass a wide variety of benign and malignant tumors. In this retrospective study, we report the clinical and histological features of 5504 eyelid skin tumors diagnosed at the Laboratory of Ophthalmopathology of the Hopital Ophtalmique Jules Gonin, Lausanne, Switzerland, between January 1989 and December 2007. Benign tumors largely predominated over malignant ones, representing 84% of cases in this series, and the 5 most frequent subtypes were squamous cell papilloma (26%), seborrheic keratosis (21%), melanocytic nevus (20%), hidrocystoma (8%), and xanthoma/xanthelasma (6%). Basal cell carcinoma was the most frequent malignant tumor (86%), followed by squamous cell carcinoma (7%) and sebaceous carcinoma (3%). For several tumor subtypes, there was a poor correlation between clinical and histological diagnosis, stressing the numerous pitfalls in the diagnosis of eyelid tumors. We further discuss our results with reference to previously published series.
Researchers ; Professionals
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