Reference : Plasma oxytocin levels and anxiety in patients with major depression
Scientific journals : Article
Human health sciences : Psychiatry
Social & behavioral sciences, psychology : Neurosciences & behavior
http://hdl.handle.net/2268/6401
Plasma oxytocin levels and anxiety in patients with major depression
English
Scantamburlo, Gabrielle mailto [Université de Liège - ULg > Département des sciences cliniques > Département des sciences cliniques]
Hansenne, Michel mailto [Université de Liège - ULg > Département des sciences cognitives > Psycho. de la personnalité et des différences individuelles >]
Fuchs, Sonia [> > > >]
Pitchot, William mailto [Centre Hospitalier Universitaire de Liège - CHU > > Psychiatrie et psychologie médicale >]
Marechal, Pierre [ > > ]
Pequeux, Christel mailto [Université de Liège - ULg > Département des sciences cliniques > Labo de biologie des tumeurs et du développement >]
Ansseau, Marc mailto [Université de Liège - ULg > Département des sciences cliniques > Psychiatrie et psychologie médicale]
Legros, Jean-Jacques mailto [Université de Liège - ULg > Département des sciences cliniques > Département des sciences cliniques >]
May-2007
Psychoneuroendocrinology
Pergamon-Elsevier Science Ltd
32
4
407-410
Yes (verified by ORBi)
0306-4530
Oxford
[en] oxytocin ; anxiety ; major depression ; neurohypophysis
[en] Cerebrospinal fluid and plasmatic levels of oxytocin (OT) have been found to change in mood disorders. In post-mortem studies, the numbers of OT-expressing neurons in the paraventricular nucleus have been reported to be increased. Moreover, OT is considered as an endogenous antistress hormone. It has also revealed antidepressive effects. OT may contribute to the dysregulation of the HPA system in major depression. The aim of the study was to assess a possible relationship between anxiety and plasma oxytocin (OT) Levels in depressive patients. Severity of depression was estimated with the Hamilton Depression Rating Scale and anxiety by using the Spielberger State-Anxiety Inventory. Results showed a significant negative correlation between oxytocin and the scored symptoms depression (r = -0.58, p = 0.003) and anxiety (r = -0.61, p = 0.005). (C) 2007 Elsevier Ltd. All rights reserved.
http://hdl.handle.net/2268/6401
10.1016/j.psyneuen.2007.01.009

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