Reference : Distribution Of Hydrophobic Residues Is Crucial For The Fusogenic Properties Of The E...
Scientific journals : Article
Life sciences : Biochemistry, biophysics & molecular biology
http://hdl.handle.net/2268/63520
Distribution Of Hydrophobic Residues Is Crucial For The Fusogenic Properties Of The Ebola Virus Gp2 Fusion Peptide
English
Adam, B. [> > > >]
Lins, Laurence mailto [Université de Liège > > Gembloux Agro-Bio Tech >]
Stroobant, V. [> > > >]
Thomas, Annick [Université de Liège - ULg > Chimie et bio-industries > Centre de Bio. Fond. - Section de Biologie moléc. et numér. >]
Brasseur, Robert mailto [Université de Liège > > Gembloux Agro-Bio Tech >]
2004
Journal of Virology
78
4
2131-6
Yes (verified by ORBi)
International
0022-538X
[en] The lipid-destabilizing properties of the N-terminal domain of the GP2 of Ebola
virus were investigated. Our results suggest that the domain of Ebola virus
needed for fusion is shorter than that previously reported. The fusogenic
properties of this domain are related to its oblique orientation at the
lipid/water interface owing to an asymmetric distribution of the hydrophobic
residues when helical.
Researchers ; Professionals
http://hdl.handle.net/2268/63520
10.1128/JVI.78.4.2131-2136.2004

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