Reference : Epithelial-to-mesenchymal transitions and circulating tumor cells.
Scientific journals : Article
Life sciences : Biochemistry, biophysics & molecular biology
http://hdl.handle.net/2268/63076
Epithelial-to-mesenchymal transitions and circulating tumor cells.
English
Bonnomet, A. [ > > ]
Brysse, Anne mailto [Université de Liège - ULg > Département des sciences cliniques > Labo de biologie des tumeurs et du développement >]
Tachsidis, A. [ > > ]
Waltham, M. [ > > ]
Thompson, E. W. [ > > ]
Polette, M. [ > > ]
Gilles, Christine mailto [Université de Liège - ULg > Département des sciences cliniques > Labo de biologie des tumeurs et du développement >]
2010
Journal of Mammary Gland Biology & Neoplasia
Kluwer Academic/Plenum Publishers
15
2
261-73
Yes (verified by ORBi)
International
1083-3021
1573-7039
New York
NY
[en] EMT ; CTC ; Metastases
[en] Epithelial-to-mesenchymal transition (EMT) phenomena endow epithelial cells with enhanced migratory and invasive potential, and as such, have been implicated in many physiological and pathological processes requiring cell migration/invasion. Although their involvement in the metastatic cascade is still a subject of debate, data are accumulating to demonstrate the existence of EMT phenotypes in primary human tumors, describe enhanced metastatic potential of EMT derivatives in animal models, and report EMT attributes in circulating tumor cells (CTCs). The relationships between EMT and CTCs remain largely unexplored, and we review here in vitro and in vivo data supporting a putative role of EMT processes in CTC generation and survival.
http://hdl.handle.net/2268/63076
10.1007/s10911-010-9174-0

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