[en] An attenuated, avirulent recombinant vaccine providing challenged protection against channel catfish virus comprises deletion of gene 50. Gene 50 encodes a secreted glycoprotein. Removal of gene 50, or replacement of gene 50 with foreign genetic material, provides a vaccine with which induces virus specific immunity against CCV disease.
Research center :
Giga-Development and Stem Cells - ULiège
Disciplines :
Biochemistry, biophysics & molecular biology
Inventor :
Vanderheijden, Nathalie
Martial, Joseph ; Université de Liège - ULiège > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire
Hanson, Larry
Language :
English
Title (54) :
Chanel catfish virus vaccine
Publication date (43-45) :
27 November 2001
Filing date (22) :
16 June 1999
Patent/publication number (10-11) :
US006322793 B1
Patent status (13) :
B
Priority number (30) :
US19990334181 19990616
International classification (IPC) (51) :
A61K 39/245; C12N 7/01; C12N 7/04; C12N 15/869
European classification (ECLA) (52) :
U.S. Cl. 424/199.1;424/205.1;424/299.1;424/817;435/235.1;435/236;435/220.1
