ORBi: Martial Joseph - Antiangiogenic peptides

Reference : Antiangiogenic peptides


	Document type :	Patent : Patent
	Discipline(s) :	Life sciences : Biochemistry, biophysics & molecular biology
	To cite this reference:	http://hdl.handle.net/2268/62854

Title :	Antiangiogenic peptides
Language :	English
Author, co-author :	Martial, Joseph [Université de Liège - ULg > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire >]
	Struman, Ingrid [Université de Liège - ULg > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire >]
	Nguyen, Ngoc-Quynh-Nhu [Université de Liège - ULg > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire >]
	Brasseur, Robert [Université de Liège - ULg > > Gembloux Agro-Bio Tech >]
	Lins, Laurence [Université de Liège - ULg > > Gembloux Agro-Bio Tech >]
Publication date :	14-Feb-2008
Creation date :	2005-08-11
Publisher :	United States
Patent/publication number (10-11) :	US 7,655,626 B2
Priority number (30) :	04103920
Report number :	B
Country :	United States
Depositor :	MARTIAL J. STRUMAN I. NGUYEN N. BRASSEUR R. LINS L.
International classification (IPC) (51) :	A61K 38/00, 31/7088, 38/10, 38/16, 38/22, A61P 15/00, 35/00,C07K 14/47, 14/61,7/08
European classification (ECLA) (52) :	U.S. Cl. 514/12, 514/14, 514/2, 514/327, 514/44, 530/324, 530/326
International protection: country codes (81) :	US
European protection: country codes (84) :	UE
Keywords :	[en] Antiangiogenic ; Peptides
Abstract :	[en] The present invention refers to a pharmaceutical composition comprising an isolated antiangiogenic peptide or a recombinant protein comprising the antiangiogenic peptide, wherein the peptide is between 11 and 40 amino acids in length and having antiangiogenic activity, the peptide comprising the amino acid sequence: X1-X2-X3-X4-X5-X6-X7-X8-X9-X10-X11-X12-X13-X14, wherein X1 is any amino acid residue comptabile with forming a helix; X2 is an amino acid redisue of : Leu, Ile, Val; X3 is an amino acid residue of: Arg, Lys, His, Ser, Thr; X4 is an amino acid residue of: Ile, Leu, Val; X5 is any amino acid residue compatible with forming a helix; X6 is an amino acid residue of: Leu, Ile, Val; X7 is an amino acid residue of: Leu, Ile, Val, Ser, Thr; X8 is any amino acid residue compatible with forming a helix; X9 is any amino acid residue compatible with forming a helix; X10 is an amino acid residue of: Gln, Glu, Asp, Arg, His, Lys, Asn; X11 is an amino acid residue of: Ser, Thr; X12 is an amino acid residue of: Trp, Tyr, Phe; X13 is an animo acid residue of Leu, Ile, Val, Asn, Gln; X14 is an amino acid residue of: Glu, Gln, Asp, Asn.
Research units :	Giga-Cancer
Permalink :	http://hdl.handle.net/2268/62854

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