Reference : Plasmatic cystatin C for the estimation of glomerular filtration rate in intensive ca...
Scientific journals : Article
Human health sciences : Anesthesia & intensive care
http://hdl.handle.net/2268/6281
Plasmatic cystatin C for the estimation of glomerular filtration rate in intensive care units
English
Delanaye, Pierre mailto [Centre Hospitalier Universitaire de Liège - CHU > > Néphrologie >]
Lambermont, Bernard mailto [Centre Hospitalier Universitaire de Liège - CHU > > Frais communs médecine >]
Chapelle, Jean-Paul mailto [Université de Liège - ULg > Département de pharmacie > Chimie médicale >]
Gielen, Jacques [ > > ]
Gérard, Paul mailto [Université de Liège - ULg > Département de mathématique > Statistique (aspects expérimentaux) >]
Rorive, Georges mailto [Université de Liège - ULg > Département des sciences cliniques > Département des sciences cliniques >]
May-2004
Intensive Care Medicine
Springer-Verlag
30
5
980-983
Yes (verified by ORBi)
International
0342-4642
New York
[en] creatinine ; critical care ; cystatin C ; glomerular filtration rate ; kidney function tests
[en] OBJECTIVE: To compare the sensitivity of cystatin C and creatinine in detecting decreased glomerular filtration rate. DESIGN: Prospective observational study. SETTING: Medical intensive care unit at a university hospital. PATIENTS AND PARTICIPANTS: Fourteen patients hospitalised in a medical intensive care unit. INTERVENTIONS: Cystatin C and creatinine plasmatic levels were measured in 40 blood samples taken with an interval of at least 24 h. MEASUREMENTS AND RESULTS: Glomerular filtration rate was estimated by creatinine clearance using 24-h urine collection and the classical Cockcroft-Gault equation. The ability of cystatin C to detect a glomerular filtration rate under 80 ml/min per 1.73 m(2) was significantly better than that of creatinine ( p<0.05). CONCLUSIONS: Cystatin C, a new plasmatic marker of renal function, could be used to detect renal failure in intensive care in the future.
http://hdl.handle.net/2268/6281
http://www.springerlink.com/content/2fefg7tvgunbyt0e/
All our thank to Springer Verlag. The original publication is available at www.springerlink.com

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