Reference : Immunohistochemical expression of epidermal growth factor receptors in nuclei of a su...
Scientific journals : Article
Life sciences : Biochemistry, biophysics & molecular biology
http://hdl.handle.net/2268/62645
Immunohistochemical expression of epidermal growth factor receptors in nuclei of a subpopulation of keratinocytes and sweat gland cells.
English
Pierard, Claudine [Centre Hospitalier Universitaire de Liège - CHU > > Dermatopathologie >]
Colige, Alain mailto [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Laboratoire des tissus conjonctifs >]
Arrese Estrada, Jorge [Centre Hospitalier Universitaire de Liège - CHU > > Dermatopathologie >]
Lapiere, C. M. [> > > >]
Pierard, Gérald mailto [Centre Hospitalier Universitaire de Liège - CHU > > Dermatopathologie >]
1991
Dermatologica
Karger
183
1
7-9
Yes (verified by ORBi)
International
0011-9075
Basel
Switzerland
[en] Cell Membrane/chemistry ; Cell Nucleus/chemistry ; Humans ; Immunohistochemistry ; Keratinocytes/chemistry/ultrastructure ; Receptor, Epidermal Growth Factor/analysis ; Sweat Glands/chemistry/ultrastructure
[en] We have raised a polyclonal antibody to the 170-kD epidermal growth factor receptor. We found an intercellular pattern of immunoreactivity in the epidermis as well as a positivity of the cytoplasm of keratinocytes and eccrine secretory cells. In some samples, a nuclear labelling was evidenced in these type of cells. There is a close resemblance in the topographical distribution of these cells with nuclear labelling and those synthesizing DNA under phytohaemagglutinin stimulation.
Researchers
http://hdl.handle.net/2268/62645

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